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- 66Chemical and Materials Engineering, Department of
- 62Chemical and Materials Engineering, Department of/Research Articles and Materials (Chemical and Materials Engineering)
- 8Surgery, Department of
- 8Surgery, Department of/Orthopaedic Surgery
- 4Chemical and Materials Engineering, Department of/Process Systems Engineering
- 1ERA General Collection
- 10Rapid Solidification
- 9Impulse Atomization
- 5Articular cartilage
Poor control of hot strip mill loopers degrades strip width and gauge, and may even lead to mill breakdowns due to instability. In this study, dynamics of the looper-strip system and the control challenges it poses are discussed, and covariance control theory is applied to variance control design...
This brief manuscript introduces the subject of thermodynamics and the papers of the special issue on thermodynamic aspects of cryobiology. Thermodynamic terminology is defined for the non-specialist.
Large articular cartilage defects have proven difficult to treat and often result in osteoarthritis of the affected joint. Cryopreservation of articular cartilage can provide an increased supply of tissues for osteochondral allograft but cryoprotective agents are required; however, few studies...
Statistical prediction of the vitrifiability and glass stability of multi-component cryoprotective agent solutions.Download
Long-term biologic storage of articular cartilage has proven elusive due to cellular degradation over time or acute damage during attempts at cryopreservation. Vitrification is one option that may result in successful cryopreservation but difficulty with cryoprotective agent (CPA) toxicity at...
The multisolute osmotic virial equation is the only multisolute thermodynamic solution theory that has been derived from first principles and can make predictions of multisolute solution behaviour in the absence of multisolute solution data. Other solution theories either (i) include simplifying...
Real-time optimization systems have become a common tool, in the continuous manufacturing industries, for improving process performance. Typically, these are on-line, steady-state, model-based optimization systems, whose eﬀectiveness depends on a large number of design decisions. The work...
The book provides an introduction to Athabasca oil sands describing their reserves and bitumen recovery methods. A summary of interfacial science is provided with analysis of interfacial interactions relevant to the understanding of bitumen recovery in an aqueous environment. Physical and...
Background Vitrification is a method of cryopreservation by which cells and tissues can be preserved at low temperatures using cryoprotective agents (CPAs) at high concentrations (typically ⩾6.0 M) to limit the harmful effects of ice crystals that can form during cooling processes. However, at...
Articular cartilage injuries do not heal and large defects result in osteoarthritis with major personal and socioeconomic costs. Osteochondral transplantation is an effective treatment for large joint defects but its use is limited by the inability to store cartilage for long periods of time....
In previous research, we successfully cryopreserved intact human articular cartilage on its bone base with high chondrocyte viability using a vitrification protocol that entailed sequential exposure to several cryopreserving agents (CPAs) at lowering temperatures resulting in a high final...