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Skip to Search Results- 83Gänzle, Michael G.
- 40Field, Catherine J.
- 31Chen, Guanqun
- 29Stothard, Paul
- 24Weselake, Randall J.
- 21Prado, Carla M.
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2014
Chakrabarti, Subhadeep, Jahandideh, Forough, Wu, Jianping
Chronic diseases such as atherosclerosis and cancer are now the leading causes of morbidity and mortality worldwide. Inflammatory processes and oxidative stress underlie the pathogenesis of these pathological conditions. Bioactive peptides derived from food proteins have been evaluated for...
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Formation of taste-active amino acids, amino acid derivatives and peptides in food fermentations – A review
Download2016-11-01
Zhao, Cindy J., Schieber, Andreas, Gänzle, Michael G.
Fermented foods are valued for their rich and complex odour and taste. The metabolic activity of food-fermenting microorganisms determines food quality and generates odour and taste compounds. This communication reviews the formation of taste-active amino acids, amino acid derivatives and...
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Formulating food protein-stabilized indomethacin nanosuspensions into pellets by fluid-bed coating technology: Physical characterization, redispersibility, and dissolution
Download2013
Yin, Lifang, Wu, Wei, He, Wei, Chen, Lingyun, Lu, Yi, Qi, Jianping
Background: Drug nanosuspensions are very promising for enhancing the dissolution and bioavailability of drugs that are poorly soluble in water. However, the poor stability of nanosuspensions, reflected in particle growth, aggregation/agglomeration, and change in crystallinity state greatly...
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2004
Zhang, Chen-Yu, Chan, Catherine B., Koshkin, Vasilij, Wheeler, Michael B., Lowell, Bradford B., Joseph, Jamie W., Saleh, Monique C., Sivitz, William I.
Chronic exposure to elevated free fatty acids (lipotoxicity) induces uncoupling protein (UCP2) in the pancreatic β-cell, and therefore a causal link between UCP2 and β-cell defects associated with obesity may exist. Recently, we showed that lipid treatment in vivo and in vitro in UCP2(–/–)...
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2008-01-01
Yang, Rong-Cai, Álvarez-Castro, José M.
Mapping quantitative trait loci (QTL) is often based on a functional or statistical model of gene action involving two alleles per locus. Such model is adequate for mapping populations derived from a cross between two inbred lines as in many plants and some laboratory animals and for di-allelic...
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Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis
Download2011
Siloto, Rodrigo M. P., Snyder, Crystal L., Liu, Qin, Weselake, Randall J.
Acyl-CoA:diacylglycerol acyltransferase (EC 2.3.1.20) is a membrane protein present mainly in the endoplasmic reticulum. It catalyzes the final and committed step in the biosynthesis of triacylglycerol, which is the principal repository of fatty acids for energy utilization and membrane...
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Functional characterization of sucrose phosphorylase and scrR, a regulator of sucrose metabolism in Lactobacillus reuteri
Download2013-01-01
Teixeira, Januana S., Abdi, Reihaneh, Su, Marcia Shu-Wei, Schwab, Clarissa, Gänzle, Michael G.
Lactobacillus reuteri harbours alternative enzymes for sucrose metabolism, sucrose phosphorylase, fructansucrases, and glucansucrases. Sucrose phosphorylase and fructansucrases additionally contribute to raffinose metabolism. Glucansucrases and fructansucrases produce exopolysaccharides as...
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Ganglioside composition of differentiated Caco-2 cells resembles human colostrum and neonatal rat intestine
Download2009
Field, Catherine J., Schnabl, Kareena L., Clandinin M. Thomas
Gangliosides are glycosphingolipids found in cell membranes and human milk with important roles in cell proliferation, differentiation, growth, adhesion, migration, signalling and apoptosis. Similar changes in ganglioside composition occur during embryonic development, lactation and cancer cell...
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Gene coexpression clusters and putative regulatory elements underlying seed storage reserve accumulation in Arabidopsis
Download2011
Peng, Fred Y., Weselake, Randall J.
Background In Arabidopsis, a large number of genes involved in the accumulation of seed storage reserves during seed development have been characterized, but the relationship of gene expression and regulation underlying this physiological process remains poorly understood. A more holistic view of...
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Gene-expression profiling of calves 6 and 9 months after inoculation with Mycobacterium avium subspecies paratuberculosis
Download2014
David, Joel, De Buck, Jeroen, Barkema, Herman W., Guan, Leluo
Early detection of Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is essential to reduce transmission; consequently, new diagnostic techniques and approaches to detect MAP or markers of early MAP infection are being explored. The objective was to identify...