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- 11Computing Science, Department of/Technical Reports (Computing Science)
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- 3Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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2006
Wagner, James, Tegos, Theodore, Wan, Xiang, Lin, Guohui
Technical report TR06-10. Background: Accurately quantifying the signature information of chemical shifts provides a foundation for accurate and complete sequential resonance assignment in protein NMR spectroscopy. A nearly complete assignment is a prerequisite for three dimensional protein ...
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Fall 2019
The manufacturing sector is of importance to Canada’s economic vitality. However, given the phenomenon of globalization, low trade barriers, and advances in technology, there has been a decline in manufacturing’s share of the Canadian economy. Today, Canadian manufacturing companies are striving...
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Fall 2011
High-throughput single nucleotide polymorphism (SNP) genotyping technologies conveniently produce large SNP genotype datasets for genome-wide linkage and association studies. Various factors, from array design and hybridization, can give rise to a certain percentage of missing calls, and the...
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2003
Chen, Zhi-Zhong, Xu, Ying, Wen, Jianjun, Lin, Guohui, Jiang, Tao, Xu, Dong, Rizzi, Romeo
Technical report TR03-07. Protein NMR peak assignment refers to the process of assigning a group of \"spin systems\" obtained experimentally to a protein sequence of amino acids. The automation of this process is still an unsolved and challenging problem in NMR protein structure determination....
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Fall 2017
In this dissertation, I focus on the study of genotype imputation in population data. Genotype imputation is a process of inferring missing values for genotype data and has been extended to predicting “untyped” genotypes for samples in low-density chips with a reference population assayed using...
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2005
Xu, Dong, Wu, Xiaomeng, Wan, Xiu-Feng, Lin, Guohui, Gang, Wu
Technical report TR05-06. The availability of complete genomic sequences allows us to infer the evolutionary footprints between species in a global strategy. However, the length of these genomic sequences poses a challenge on computational efficiency and optimality of information representation...
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2015
Stothard, Paul, Wang, Yining, Lin, Guohui, Wylie, Tim
Background Despite ongoing reductions in the cost of sequencing technologies, whole genome SNP genotype imputation is often used as an alternative for obtaining abundant SNP genotypes for genome wide association studies. Several existing genotype imputation methods can be efficient for this...