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Spring 2017

Rossolatos, David

Cannabis use is a known risk factor for the development of psychotic disorders. Clinical and preclinical genetic studies provide growing evidence that genes related to dopamine signalling and neuroprotection, like COMT, are implicated in the cannabis-psychosis association. Considering the burden...

Fall 2017

Perrott, Laurel A

The grain yields of feed barley (Hordeum vulgare L.) have increased at a slower rate than the yields of other major crops in Alberta, and seeded barley acres have declined over the past 20 years. Agronomic management and cultivar specific responses to management may provide solutions to increase...

2012

Xia, Y., Zhang, X., Mu, Z., Li, X., Wang, T., Qu, J., Chen, H., Li, K., Zhu, L., Wang, L., Liu, Y., Zhang, K., Guan, J., Wu, H., Jiang, A., Yin, G., Xi, D., Shuai, S., Lang, Q., Jiang, Y., Wang, Z., Luo, Z., Xiao, H., Li, Y., Huang, S., Gu, Y., Beck, S., Ma, J., Wang, H., Jing, L., Plastow, G. S., Jiang, Z., Gao, X., Chen, L., Tang, G., Wang, J., Li,R., Li, M., Mai, M., Wang, Y., Wang, X., Zhong, Z., Nie, J., Zhou, S., Yang, H., Yi, N., Li, N.

It is evident that epigenetic factors, especially DNA methylation, have essential roles in obesity development. Here, using pig as a model, we investigate the systematic association between DNA methylation and obesity. We sample eight variant adipose and two distinct skeletal muscle tissues from...

Spring 2020

Nami Mollalou, Babak

HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...

Fall 2010

Mujibi, Fidalis

Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested,...

Fall 2009

Ferreira Marques, Elisa

Genetic improvements in beef and dairy cattle can bring significant advances in satisfying the global food demand, which is expected to double by 2050. Several DNA markers have been identified on bovine chromosome 14 (BTA14), but low mapping resolution prevents their refinement for identification...

2000-08-01

Wang, Jian, Burnett, John R., Near, Susan, Young, T. Kue, Zinman, Bernard, Hanley, Anthony J. G., Connelly, Philip W., Harris, Stewart B., Hegele, Robert A.

"Mutations in ABCA1, a member of the ATP-binding cassette family, have been shown to underlie Tangier disease (TD) and familial hypoalphalipoproteinemia (FHA), which are genetic disorders that are characterized by depressed concentrations of plasma high density lipoprotein (HDL) cholesterol. An...

2007-12-01

Lahiry, Piya, Ban, Matthew R., Pollex, Rebecca L., Sawyez, Cynthia G., Huff, Murray W., Young, T. Kue, Bjerregaard, Peter, Hegele, Robert A.

"Objectives: We undertook studies of the association between common genomic variations in APOC3, APOA5, APOE and PON1 genes and variation in biochemical phenotypes in a sample of Greenlanders. Study Design: Genetic association study of quantitative lipoprotein traits. Methods: In a sample of...

2019-01-01

Nair, Sindhu G., Loppnow, Glen R.

It has been well established that mutations in K-Ras and N-Ras proto-oncogenes can convert them into active oncogenes. Current molecular cancer research has been focused on determining the key steps by which cellular genes become oncogenes and not on the underlying and fundamental chemical damage...

1978

Elisens, Wayne J.

Masters thesis. Suggests elevation of five taxa of Oxytropis campestris to species status, based on chromosome studies.