Application of genetic markers for evaluation of residual feed intake in beef cattle

• Author / Creator

  Mujibi, Fidalis

• Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested, leading to low accuracies of estimated breeding values (EBV). Three studies were conducted to demonstrate the usefulness of including DNA marker information in RFI genetic evaluations. In the first study, the effect of period of testing on RFI was assessed. Beef cattle steers were tested for feed intake, with different cohorts tested in the fall-winter and winter-spring seasons. Seasonal differences were detected although these were confounded by differences in age and weight among the seasons. Additionally, mean EBV accuracy obtained was low, ranging between 0.47 and 0.51, implying that strategies to increase this accuracy are necessary. In the 2nd study, a suite of genetic markers predictive of RFI, DMI and ADG were pre-selected using single marker regression analysis and the top 100 SNPs analyzed further in 5 replicates of the training data to provide prediction equations for RFI, DMI and ADG. Cumulative marker phenotypes (CMP) were used to predict trait phenotypes and accuracy of prediction ranged between 0.007 and 0.414. Given that this prediction accuracy was lower than the polygenic EBV accuracy, the CMP would need to be combined with EBV for effective marker assisted selection. In study 3, genomic selection (GS) theory and methodology were used to derive genomic breeding values (GEBV) for RFI, DMI and ADG. The accuracy of prediction obtained with GEBV was low, ranging from 0.223 to 0.479 for marker panel with 200 SNPs, and 0.114 to 0.246 for a marker panel with 37,959 SNPs, depending on the GS method used. The results from these studies demonstrate that the utility of genetic markers for genomic prediction of RFI in beef cattle may be possible, but will likely be more effective if a tool that combines GEBV with traditional BLUP EBV is used for selection.

• Subjects / Keywords

  • Markers
  • Evaluation
  • Genetics
  • Cattle
  • RFI
  • SNP
  • Beef

• Graduation date

  Fall 2010

• Type of Item

  Thesis

• Degree

  Doctor of Philosophy

• DOI

  https://doi.org/10.7939/R3G41Z

• License

  This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.