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- 12Phosphatidylcholine
- 10Triacylglycerol
- 7Triacylglycerol biosynthesis
- 4Linum usitatissimum
- 3Brassica napus
- 14Chen, Guanqun
- 12Xu, Yang
- 9Weselake, Randall J.
- 7Caldo, Kristian Mark P.
- 5Mietkiewska, Elzbieta
- 5Pan, Xue
- 19Agricultural, Food and Nutritional Science, Department of
- 19Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 12Graduate and Postdoctoral Studies (GPS), Faculty of
- 12Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Physaria fendleri and Ricinus communis LCAT-like phospholipases selectively cleave hydroxy acyl chains from phosphatidylcholine
Download2020-10-27
Xu, Yang, Caldo, Kristian Mark P., Singer, Stacy D., Mietkiewska, Elzbieta, Greer, Michael S., Tian, Bo, Dyer, John M., Smith, Mark, Zhou, Xue-Rong, Qiu, Xiao, Weselake, Randall J., Chen, Guanqun
Producing hydroxy fatty acids (HFAs) in transgenic crops represents a promising strategy to meet our demands for specialized plant oils with industrial applications. The expression of Ricinus communis (castor) OLEATE 12-HYDROXYLASE (RcFAH12) in Arabidopsis has resulted in only...
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Plant acyl-CoA:lysophosphatidylcholine acyltransferases (LPCATs) have different specificities in their forward and reverse reactions
Download2013
Heinz, Ernst, Zhou, Xue-Rong, Banas, Antoni, Green, Allan, Jasieniecka, Katarzyna, Weselake, Randall, Smith, Mark A., Stymne, Sten, Bayon, Shen, Zou, Jitao, Lager, Ida, Dyer, John M., Shockey, Jay M., Yilmaz, Jenny L., Wang, Peng, Kazachkov, Michael
Acyl-CoA:lysophosphatidylcholine acyltransferase (LPCAT) enzymes have central roles in acyl editing of phosphatidylcholine (PC). Plant LPCAT genes were expressed in yeast and characterized biochemically in microsomal preparations of the cells. Specificities for different acyl-CoAs were similar...
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Plant sn‐Glycerol‐3‐Phosphate Acyltransferases: Biocatalysts Involved in the Biosynthesis of Intracellular and Extracellular Lipids
Download2018-05-31
Jayawardhane, Kethmi N., Singer, Stacy D., Weselake, Randall J., Chen, Guanqun
Acyl‐lipids such as intracellular phospholipids, galactolipids, sphingolipids, and surface lipids play a crucial role in plant cells by serving as major components of cellular membranes, seed storage oils, and extracellular lipids such as cutin and suberin. Plant lipids are also widely used to...
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Properties and Biotechnological Applications of Acyl‐CoA:diacylglycerol Acyltransferase and Phospholipid:diacylglycerol Acyltransferase from Terrestrial Plants and Microalgae
Download2018-07-30
Xu, Yang, Caldo, Kristian Mark P., Pal‐Nath, Dipasmita, Ozga, Jocelyn, Lemieux, M. Joanne, Weselake, Randall J., Chen, Guanqun
Triacylglycerol (TAG) is the major storage lipid in most terrestrial plants and microalgae, and has great nutritional and industrial value. Since the demand for vegetable oil is consistently increasing, numerous studies have been focused on improving the TAG content and modifying the fatty‐acid...
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Role of TG Lipases, Arylacetamide Deacetylase and Triacylglycerol Hydrolase, in Hepatitis C Virus Life Cycle
DownloadSpring 2013
Hepatitis C virus (HCV) is a major cause of chronic liver disease, including liver steatosis, fibrosis, cirrhosis, and hepatocellular carcinoma. It has become apparent that the targeting of lipid droplets (LDs) by the HCV core protein and the Very Low Density Lipoprotein (VLDL) secretory pathway...
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Structural and Biochemical Changes in Loblolly Pine (Pinus taeda L.) Seeds during Germination and Early Seedling Growth. II. Storage Triacylglycerols and Carbohydrates
Download1999
Abstract: Triacylglycerols (TAGs) comprised 59% of the total storage reserve in mature loblolly pine (Pinus taeda L.) seeds; 80% of these TAGs were stored in the megagametophyte. The TAG breakdown in the seedling was initiated before radicle emergence (during germination), while in the...
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Substrate preferences of long-chain acyl-CoA synthetase and diacylglycerol acyltransferase contribute to enrichment of flax seed oil with a-linolenic acid
Download2018-04-01
Xu, Yang, Holic, Roman, Li, Darren, Pan, Xue, Mietkiewska, Elzbieta, Chen, Guanqun, Ozga, Jocelyn, Weselake, Randall J.
Seed oil from flax (Linum usitatissimum) is enriched in a-linolenic acid (ALA; 18:3?9cis,12cis,15cis), but the biochemical processes underlying the enrichment of flax seed oil with this polyunsaturated fatty acid are not fully elucidated. Here, a potential process involving the catalytic actions...
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Substrate preferences of long-chain acyl-CoA synthetase and diacylglycerol acyltransferase contribute to enrichment of flax seed oil with α -linolenic acid
Download2018-01-01
Xu, Yang, Holic, Roman, Li, Darren, Mietkiewska, Elzbieta, Chen, Guanqun, Ozga, Jocelyn, Weselake, Randall
Seed oil from flax ( Linum usitatissimum ) is enriched in α -linolenic acid (ALA; 18:3 Δ 9 cis ,12 cis ,15 cis) but the biochemical processes underlying the enrichment of flax seed oil with this polyunsaturated fatty acid are not fully elucidated. Here, a potential process involving the catalytic...
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The role of de novo phosphatidylcholine synthesis in the gut-liver axis and intestinal homeostasis
DownloadSpring 2023
The intestine and liver are in constant communication to maintain lipid processes and to prevent disease states such as non-alcoholic fatty liver disease (NAFLD) and colitis. Phosphatidylcholine (PC) can be synthesized in the liver by the CDP-choline pathway or the phosphatidylethanolamine...
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2014-01-01
Lewis, Erin D., Kosik, Sarah J., Zhao, Yuan-Yuan, Jacobs, René L., Curtis, Jonathan M., Field, Catherine J.
Estimating dietary choline intake can be challenging due to missing foods in the current United States Department of Agriculture (USDA) database. The objectives of the study were to quantify the choline-containing moieties and the total choline content of a variety of pulses available in North...