Journal Articles (Agricultural, Food and Nutritional Science)
Items in this Collection
- 49Gänzle, Michael G.
- 40Field, Catherine J.
- 29Stothard, Paul
- 26Chen, Guanqun
- 23Weselake, Randall J.
- 21Proctor, Spencer D.
Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimersDownload
Anti-oxidant capacity is crucial defence against environmental or endogenous oxidative stress. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that plays a key defensive role against oxidative and cytotoxic stress and cellular senescence. However, Nrf2...
Acyl-CoA-binding and self-associating properties of a recombinant 13.3 kDa N-terminal fragment of diacylglycerol acyltransferase-1 from oilseed rapeDownload
Nykiforuk, Cory L., Szarka, Steve J., Laroche, André, Mosimann, Steven C., Burton, Tracy L., Thibault, Benjamin J., Boora, Parveen S., Madhavji, Milan, Foroud, Nora A., Moloney, Maurice M., Wiehler, William B., Patterson, Nii A., Weselake, Randall J., Furukawa-Stoffer, Tara L.
Background Diacylglycerol acyltransferase (DGAT, EC 22.214.171.124) catalyzes the acyl-CoA-dependent acylation of sn-1, 2-diacylglycerol to generate triacylglycerol and CoA. The deduced amino acid sequence of cDNAs encoding DGAT1 from plants and mammals exhibit a hydrophilic N-terminal region followed...
Adaptation to high grain diets proceeds through minimal immune system stimulation and differences in extracellular matrix protein expression in a model of subacute ruminal acidosis in non-lactating dairy cowsDownload
Problem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with...
The recent technological innovations in the area of functional genomics, gene expression/transcriptomic profiling can provide new insights to understand the molecular basis of adipogenesis. The focus of this review is to highlight the recent advances in our understanding of the complex interplay...
Enthalpy relaxation experiments were conducted in freeze-dried raspberry powder at 5, 10 and 15 °C below its onset glass transition temperature (Tgi) using differential scanning calorimetry (DSC). The statistical differences in Tgi for the raspberry powders aged at (Tgi − 5), (Tgi − 10), and (Tgi...
The objectives of this study were to evaluate metabolic and innate immunity alterations in the blood of transition dairy cows before, during, and after diagnosis of lameness during periparturient period. Blood samples were collected from the coccygeal vain once per week before morning feeding...
Altered microRNA expression in bovine subcutaneous and visceral adipose tissues from cattle under different dietDownload
Background MicroRNAs (miRNAs) are a class of molecular regulators found to participate in numerous biological processes, including adipogenesis in mammals. This study aimed to evaluate the differences of miRNA expression between bovine subcutaneous (backfat) and visceral fat depots (perirenal...
Host resistance to bacterial infections is thought to be dictated by host genetic factors. Infections by the natural murine enteric pathogen Citrobacter rodentium (used as a model of human enteropathogenic and enterohaemorrhagic E. coli infections) vary between mice strains, from mild...
Analysis of genotype-environment interactions from a genome-wide survey of quantitative trait loci in a barley populationDownload
The presence of genotype-environment interactions (GE) leads to the imperfect genetic correlation between the measurements of the same trait in different environments, thereby limiting the ability of plant breeders to identify superior breeding lines or best cultivars across the environments. We...
Analysis of linear and nonlinear genotype × environment interaction
The usual analysis of genotype × environment interaction (G × E) is based on the linear regression of genotypic performance on environmental changes (e.g., classic stability analysis). This linear model may often lead to lumping together of the non-linear responses to the whole range of...