SearchSkip to Search Results
- 5AlZahal, Ousama
- 5Dionissopoulos, Louis
- 5McBride, Brian W.
- 5Steele, Michael A.
- 2Greenwood, Sabrina L.
- 2Laarman, Anne H.
A characterization of inflammatory and structural markers within the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattleDownload
The objective of this study was to characterize the mRNA and protein expression of inflammatory and structural genes in the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattle. A total of 16 rumen-fistulated, lactating Holstein dairy cattle (618±35 kg of body weight,...
Adaptation to high grain diets proceeds through minimal immune system stimulation and differences in extracellular matrix protein expression in a model of subacute ruminal acidosis in non-lactating dairy cowsDownload
Problem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with...
Butyrate and subacute ruminal acidosis affect abundance of membrane proteins involved with proton and short chain fatty acid transport in the rumen epithelium of dairy cowsDownload
The objective of this study was to elucidate the effects of butyrate on the Short Chain Fatty Acids (SCFA) membrane transport proteins and proton membrane transport proteins in the rumen epithelium. Sixteen mid-lactation cows were fed a 44% Non-Fibre Carbohydrate (NFC) diet and divided into a...
Butyrate-mediated genomic changes involved in the non-specific host defenses, matrix remodelling and the immune response in the rumen epithelium of cows afflicted with subacute ruminal acidosisDownload
Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by...
To understand how the capacity for fat metabolism (uptake, synthesis, modification) changes in rumen epithelia immediately before and after onset of lactation in dairy cows, rumen fluid Short Chain Fatty Acid (SCFA) concentrations and mRNA expression profiles of rumen epithelia was determined in...