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Skip to Search Results- 74Gänzle, Michael G.
- 40Field, Catherine J.
- 31Chen, Guanqun
- 29Stothard, Paul
- 24Weselake, Randall J.
- 21Proctor, Spencer D.
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2015-01-01
Zheng, Jinshui, Gänzle, Michael G., Lin, Xiaoxi B., Ruan, Lifang, Sun, Ming
Human commensal microbiota are an important determinant of health and disease of the host. Different human body sites harbour different bacterial microbiota, bacterial communities that maintain a stable balance. However, many of the factors influencing the stabilities of bacterial communities...
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Do sugar-sweetened beverages cause adverse health outcomes in children? A systematic review protocol
Download2014
Ziegler, Paula, Hamel, Candyce, Gow, Robert, Hutton, Brian, Pound, Catherine, Hadjiyannakis, Stasia, Sharma, Arya, Myers, Esther, Willows, Noreen, Singh, Kavita, Fenton, Shannon, Salewski, Erinn, Shrier, Ian, Ansari, Mohammed T., Stevens, Adrienne, O'Hara, Kathryn, Moher, David, Bjerre, Lise M., Tremblay, Mark
Background Cardiovascular disease and type 2 diabetes are examples of chronic diseases that impose significant morbidity and mortality in the general population worldwide. Most chronic diseases are associated with underlying preventable risk factors, such as elevated blood pressure, high blood...
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Does IGFR1 inhibition result in increased muscle mass loss in patients undergoing treatment for pancreatic cancer?
Download2014
Shroff, R., Katz, M. H., Overman, M. J., Khalil, M., Lieffers, J., Varadhachary, G. R., Fogelman, D., Javle, M. , Holmes, H., Prado, C. M.
BackgroundIGF-1 plays a role in the growth of multiple tumor types, including pancreatic cancer. IGF-1 also serves as a growth factor for muscle. The impact of therapeutic targeting of IGF-1 on muscle mass is unknown.MethodsWe evaluated muscle mass at L3 in patients enrolled in a randomized phase...
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Down-regulation of hypothalamic pro-opiomelanocortin (POMC) expression after weaning is associated with hyperphagia-induced obesity in JCR rats overexpressing neuropeptide Y
Download2013
Diane, Abdoulaye, Pierce, W. David, Richard, Denis, Heth, C. Donald, Proctor, Spencer D., Vine, Donna F., Russell, James C.
We hypothesised that hypothalamic feeding-related neuropeptides are differentially expressed in obese-prone and lean-prone rats and trigger overeating-induced obesity. To test this hypothesis, in the present study, we measured energy balance and hypothalamic neuropeptide Y (NPY) and...
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Downregulation of key genes involved in carbon metabolism in Medicago truncatula results in increased lipid accumulation in vegetative tissue
Download2020-02-11
Wijekoon, Champa, Singer, Stacy D., Weselake, Randall J., Petrie, James R., Chen, Guanqun, Singh, Surinder, Eastmond, Peter J., Acharya, Surya N.
Alfalfa (Medicago sativa L.) is the most widely grown perennial forage crop and is a close relative of the model diploid legume Medicago truncatula Gaertn. However, use of alfalfa leads to substantial greenhouse gas emissions and economic losses related to inefficiencies in rumen fermentation....
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2023-03-01
Ford, Katherine L., Trottier, Claire F., Wismer, Wendy V., Sawyer, Michael B., Siervo, Mario, Deutz, Nicolaas E.P., Prado, Carla M., Vallianatos, Helen
Background Dietary changes often accompany management of a cancer diagnosis, but how and why patients with colorectal cancer (CRC) make dietary decisions requires further investigation. Objective To learn about patients’ food-related beliefs and understand whether and why dietary changes were...
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2006
Chang, Zhan, Hassanali, Murtaza, Wishart, David S., Stothard, Paul, Woolsey, Jennifer, Guo, AnChi, Shrivistava, Savita, Knox, Craig
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical) data with comprehensive drug target (i.e. protein) information. The database contains >4100 drug entries including >800 FDA approved small molecule and biotech drugs as well as >3200...
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Dynamics of Enterobacteriaceae and lactobacilli in model sourdoughs are driven by pH and concentrations of sucrose and ferulic acid
Download2019-01-01
Dinardo, Francesca Rita, Minervini, Fabio, De Angelis, Maria, Gobbetti, Marco, Gänzle, Michael G.
This study aimed to assess, in model sourdough fermentations, the relevance of physico-chemical features of flour for the interactions between Enterobacteriaceae and lactobacilli, and for the interactions within the latter microbial group. Initially, model sourdoughs made with white wheat flour,...
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Effect of acceptor carbohydrates on oligosaccharide and polysaccharide synthesis by dextransucrase DsrM from Weissella cibaria
Download2017-09-01
Hu, Ying, Winter, Verena, Chen, Xiao Yan, Gänzle, Michael G.
The digestibility of isomalto-oligosaccharides (IMO) as well as their metabolism by gut microbiota depends on the degree of polymerization and the ratio of α-(1→4) to α-(1→6) linkages. Both parameters are influenced by the method of production. Commercial IMO are produced by transglycosylation of...
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Effect of chitosan, and bacteriocin – Producing Carnobacterium maltaromaticum on survival of Escherichia coli and Salmonella Typhimurium on beef
Download2018-01-01
Hu, Zi Yi, Balay, Danielle, Hu, Ying, McMullen, Lynn M., Gänzle, Michael G.
The aim of this study was to investigate the synergistic effect of chitosan and bacteriocins against Escherichia coli and Salmonella in media and in lean beef. The inhibitory effects of chitosan and bacteriocins against E. coli AW1.7 and S. enterica Typhimurium in media were determined by a...