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Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization
Download2001-01-01
Khaled, Annette R., Moor, Andrea N., Li, Aiqun Q., Kim, Kyungjae, Ferris, Douglas K., Muegge, Kathrin, Fisher, Robert J., Fliegel, Larry, Durum, Scott K.
Trophic factor withdrawal induces cell death by mechanisms that are incompletely understood. Previously we reported that withdrawal of interleukin-7 (IL-7) or IL-3 produced a rapid intracellular alkalinization, disrupting mitochondrial metabolism and activating the death protein Bax. We now...
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Trophic Relations of the Red-Necked Grebe on Lakes in the Western Boreal Forest: A Stable-Isotope Analysis.
Download2004
Tonn, W. M., Klatt, P. H., Paszkowski, C. A., Gingras, B. A., Wilcox, K.
We compared trophic ecology of grebes inferred from stable-isotope analysis to that from gut contents, and compared isotopic ratios of Red-necked Grebes (Podiceps grisegena) from lakes differing in their food webs. Analyses of different grebe tissues (egg yolk and albumen, pectoral and leg...
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Tropical forest restoration within Galapagos National Park: application of a state-transition model
Download2005
Wilkinson, S.R., Schmeigelow, F.K.A., Naeth, M.A.
Current theory on non-equilibrium communities, thresholds of irreversibility, and ecological resilience suggests the goal of ecological restoration of degraded communities is not to achieve one target, but to reestablish the temporal and spatial diversity inherent in natural ecosystems. Few...
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Tuberculosis in the era of infection with the human immunodeficiency virus: Assessment and comparison of community knowledge of both infections in rural Uganda.
Download2012
Richter, M. S., Jhangri, G. S., Alibhai, A., Kipp, W., Wynne, A., Rubaale, T.
Background In Uganda, despite a significant public health burden of tuberculosis (TB) in the context of high human immunodeficiency virus (HIV) prevalence, little is known about community knowledge of TB. The purpose of this study was to assess and compare knowledge about TB and HIV in the...
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2015
Zhong, Weiming, Quigley, Christina, Klassen, John S., Fang, Hao, Jiang, Xi, Wei, Chao, Tan, Ming, Xia, Ming, Huang, Pengwei, Fan, Qiang, Zhang, Xufu
The recent discovery that human noroviruses (huNoVs) recognize sialic acids (SAs) in addition to histo-blood group antigens (HBGAs) pointed to a new direction in studying virus-host interactions during calicivirus infection. HuNoVs remain difficult to study due to the lack of an effective cell...
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Tumour-stromal interactions: Integrins and cell adhesions as modulators of mammary cell survival and transformation
Download2001
Chrenek, Micah A., Weaver, Valerie M., Wong, Paul
Stromal–epithelial interactions modulate mammary epithelial cell (MEC) growth and apoptosis by influencing cell adhesion and tissue organization. Perturbations in the mammary stroma and cell adhesion characterize breast tumors and underlie the altered tissue organization, disrupted tissue...
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2022-06-01
This paper presents a design approach for tuning autonomous driving controllers of road vehicles. In this regard, a bicycle vehicle model and a model predictive control (MPC) algorithm have been applied to the tracking-control lateral of autonomous vehicles. Additionally, in order to maximize...
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Turbidity Mitigation in an Oil Sands Pit Lake through pH Reduction and Fresh Water Addition
Turbidity Mitigation in an Oil Sands Pit Lake through pH Reduction and Fresh Water Addition
Download2018-01-01
Ho Yin Poon; Jordan T. Brandon; Xiaoxuan Yu; Ania C. Ulrich
Currently, tailings ponds are used to contain oil sands process-affected water (OSPW) and fluid fine tailings (FFT) generated from the Alberta oil sands mining operations. In 2016, the government of Alberta introduced a tailings management directive providing guidance for reclamation efforts in...
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2003
This article examines the use of all obligation clauses in security agreements and their potential to transform an unsecured claim into a more valuable secured claim upon an assignment of the unsecured claim or the security agreement. The author addresses three arguments that have been levelled...