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Skip to Search Results- 2Wu, Nathanael Lap-Yan
- 1Achal, Roshan
- 1Alam, Kazi, MM
- 1Baillie, Devin MJ
- 1Binkhathlan, Ziyad
- 1Chung, Deborah K
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Design of Macromolecular Anti-cancer Drug Delivery Systems using Molecular Dynamics Simulation
DownloadFall 2015
In recent years, the application of self-associating block copolymer based drug delivery systems has attracted increasing attention as nano-sized carriers for the encapsulation and the controlled delivery of water insoluble drugs. Most of the drug formulations are based on the “trial and error”...
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Spring 2010
In recent years, the use of self-associating block copolymer based drug delivery systems have attracted increasing attention as nanoscopic carriers for the encapsulation and the controlled delivery of water insoluble drugs. Currently, most of the drug formulations proceed by “trial and error”...
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Development of an optical biosensor based on Mach-Zehnder Interferometry for detection of Listeria monocytogenes
DownloadFall 2013
Label-free optical biosensors are widely used for the detection of pathogens due to their low-cost, real-time detection and high sensitivity. A Mach-Zehnder Interferometer (MZI) based biosensor has been developed for the detection of gram-positive bacteria, Listeria monocytogenes. An extensive...
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Development of block copolymer based nanocarriers for the solubilization and delivery of valspodar
DownloadFall 2011
One of the major causes of failure in cancer chemotherapy is multidrug resistance (MDR), where cancer cells become resistant to different types of anticancer drugs. Over-expression of membrane efflux pumps like P-glycoprotein (P-gp), which recognizes different chemotherapeutic agents and...
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Spring 2010
Nanoscale patterning of organic molecules has received considerable attention in current nanoscience for a broad range of technological applications. In order to provide a viable approach, this thesis describes catalytic stamp lithography, a novel soft-lithographic process that can easily...
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DNA-assisted Heterogeneous Integration of Micro- and Nanoelectronic Devices: Modeling, Control, and Rational Design of Selective Attachment
DownloadSpring 2018
Heterogeneous integration is an electronic packaging approach that enables the fabrication and assembly of complete electronic subsystems from components fabricated with different substrates and processes. Current commercial techniques like robotic pick-and-place, fluidic self-assembly, and...
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Spring 2020
On a perfect hydrogen-terminated Si(100)-2x1 surface, each surface silicon atom is capped with exactly one atom of hydrogen. When one of the capping hydrogen atoms is removed, the now unsatisfied orbital of the underlying silicon atom is exposed at that site. This site is better known as a...
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Spring 2016
This thesis explores the dynamics and sensing performance of silicon quantum dot (SiQD) ensembles coupled to the whispering gallery modes (WGMs) of spherical and cylindrical microcavities. The first project investigated the possibility of observing Purcell effects in an ensemble of QDs coupled to...
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Spring 2015
This thesis focuses on the photoluminescence (PL) of free-standing silicon quan- tum dots (QDs). Large changes in the emission spectrum were found to occur when the QDs were exposed to different environments while undergoing short-wavelength laser irradiation, a phenomenon that was the main focus...
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Interfacing Silicon-Based Quantum Dots with Proteins for Biological and Sensing Applications
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This dissertation presents the preparation of functional bioinorganic hybrids from silicon-based quantum dots (SiQDs) and enzymes and the use of SiQDs and green fluorescent protein as ratiometric photoluminescent sensors for nerve agents. Chapter 2 discusses the preparation of water-soluble...