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2007

Johnson, S.J., Carroll, R.T., Vidmar, J.J., Stroeher,V., Taylor, G.T., Good, A.G., DePauw, M., Lu, Z., Savidov, N.

Nitrogen (N) is the most important factor limiting crop productivity worldwide. The ability of plants to acquire N from applied fertilizers is one of the critical steps limiting the efficient use of nitrogen. To improve N use efficiency, genetically modified plants that overexpress alanine...

2003

Greiner, Russ, Poulin, B., Lu, Paul, Anvik, J., Lu, Z., Macdonell, Cam, Wishart, David, Eisner, Roman, Szafron, Duane

Technical report TR03-09. Naive Bayes classifiers, a popular tool for predicting the labels of query instances, are typically learned from a training set. However, since many training sets contain noisy data, a classifier user may be reluctant to blindly trust a predicted label. We present a...

2008

Li, R., Wang, J., Wong, G.K.S., Zheng, H., Xu, S., Clark, T., Zheng, X., Vang, S.

Background Gene conversion causes a non-reciprocal transfer of genetic information between similar sequences. Gene conversion can both homogenize genes and recruit point mutations thereby shaping the evolution of multigene families. In the rice genome, the large number of duplicated genes...

2006

Wang, W., Li, J., Liu, D., Lu, Z., Zheng, H., Wong, G., Cai, Z., Fan, C., Zhang, J., Vang, S., Long, M., Zhang, G., Wang, J., Shi, J.

Retroposition is widely found to play essential roles in origination of new mammalian and other animal genes. However, the scarcity of retrogenes in plants has led to the assumption that plant genomes rarely evolve new gene duplicates by retroposition, despite abundant retrotransposons in plants...

2007

Wang, W., Wang, H., Wong, G.K.S., Zheng, H., Clark, T., Zhang, G., Kang, L., Wang, J., Shi, J., Wang, X.

Background Insects constitute the vast majority of known species with their importance including biodiversity, agricultural, and human health concerns. It is likely that the successful adaptation of the Insecta clade depends on specific components in its proteome that give rise to specialized...

2009

Xu, J., Goebel, R. A., Cai, Z., Sabaai, H., Lin, G., Wang, Z., Wang, Y., Stothard, P.

Background The \"common disease – common variant\" hypothesis and genome-wide association studies have achieved numerous successes in the last three years, particularly in genetic mapping in human diseases. Nevertheless, the power of the association study methods are still low, in particular on...

2003

Greiner, Russell, Wishart, David, Eisner, Roman, Lu, Z., Lu, Paul, Macdonell, Cam, Poulin, B., Szafron, Duane, Anvik, J.

Technical report TR03-14. Identifying the destination or localization of proteins is key to understanding their function and facilitating their purification. A number of existing computational prediction methods are based on sequence analysis. However, these methods are limited in scope, accuracy...

2003

Lu, Z., Eisner, Roman, Lu, Paul, Macdonell, Cam, Szafron, Duane, Greiner, Russell, Poulin, B., Wishart, David, Anvik, J., Habibi-Nazhad, B.

Technical report TR03-05. Modern sequencing technology now permits the sequencing of entire genomes, leading to thousands of new gene sequences in need of detailed annotation. It is too time consuming to predict the properties of each protein sequence manually and to organize the results of many...

2004

Poulin, P., Lu, Z., Fyshe, A., Szafron, D., Meeuwis, D., Anvik, J., Wishart, D.S., Grenier, R., Eisner, R., Macdonell, C., Lu, P.