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Evolving In Vitro and In Silico Methods for Predicting Performance in Respiratory Drug Delivery Applications
DownloadSpring 2022
The overarching theme of this work is the investigation and development of in vitro and in silico methods used to characterize inhaled pharmaceutical aerosols. The ultimate aim is to expand and strengthen the links between applied science and clinical practice for inhaled medications. Chapter 1...
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Evaluation of Frailty Assessment Tools and their Measurement Properties in Chronic Kidney Disease
DownloadSpring 2022
Background: Frailty is three to seven times more common in people with chronic kidney disease (CKD) than in those with normal kidney function. Although frailty and its impact in CKD is well-recognized, the measurement properties of the tools used to assess this syndrome are not known. The aim of...
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Spring 2022
Managing fluid fine tailings (FFT) is a defining challenge of the oil sands industry in Alberta due to low solids content, and extremely slow self-weight consolidation. One technology to increase the solids content of these tailings is centrifugation to produce centrifuged fluid fine tailings...
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Effects of retrogressive thaw slumping on particulate organic carbon dynamics in the Northwest Territories, Canada
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Climate change is increasing the frequency and intensity of thermokarst and accelerating the delivery of terrestrial organic material from previously sequestered sources to aquatic systems, where it is subject to further biochemical alteration. Rapid climate change in the glacially conditioned...
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Les effets de la pandémie de la COVID-19 sur le bien-être au travail : Perspectives des enseignants albertains
DownloadSpring 2022
Dans un contexte sociétal fortement perturbé par la COVID-19, les préoccupations des enseignants concernant leur santé mentale peuvent être exacerbées. L'objectif de cette recherche est d’identifier les pratiques de leadership qui peuvent permettre aux administrateurs scolaires de favoriser le...
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Spring 2022
The ever-growing market share of electrical transportation and energy storage stations has led to a demand surge for lithium-ion batteries (LIBs). Despite their popularity in global energy storage market, an efficient, sustainable and green method that can recycle spent LIBs is also in active...
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Spring 2022
Pancreatic β-cells are paramount for optimizing insulin secretion to metabolic need. The progression from non-diabetes to type 2 diabetes (T2D) is accompanied by β-cell compensation and decompensation. While β-cell decompensation is a hallmark of overt diabetes, β-cell compensation promotes...
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Spring 2022
Automated Vehicle (AV) is a trending technology being developed with the promise to reduce traffic accidents caused by human errors. Perception plays a crucial role for Automated Driving Systems (ADS) to make safe decisions. However, local sensory data is insufficient to capture comprehensive...
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Secondary Interaction of Fracturing Fluid and Shale Plays: A Reservoir Geomechanics Approach
DownloadSpring 2022
During hydraulic fracturing in unconventional tight formations a high percentage of the injected fluid may remain in the formation and only a small portion of the fracturing fluid is typically recovered. Although spontaneous imbibition is mainly introduced as the main dominating mechanism, a...