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Development and Application of Chemical Isotope Labeling Methods and Metabolite Identification Solution for Liquid Chromatography-Mass Spectrometry-Based Metabolomics
DownloadFall 2018
Metabolomics, the comprehensive analysis of small molecules in biological specimens, has become an emerging and indispensable tool for systems biology and clinical research. Liquid chromatography-mass spectrometry (LC-MS) is a dominant analytical platform for metabolomics, featuring high...
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GEOPHYSICAL SITE CHARACTERIZATION OF THE MCQUAT LAKE SYNFORM MARY RIVER DISTRICT, BAFFIN ISLAND CANADA
DownloadSpring 2018
Arctic drilling programs are expensive and time consuming and deliver very little data regarding the local and regional geological structure. By performing multiple passive and active geophysical surveys, a better understanding of both local and regional geology can be determined. This thesis...
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Fall 2017
Metastasis is the leading cause of cancer-related deaths, yet there are no therapies that directly target this process. To identify potential therapeutic targets of metastatic dissemination, we recently completed the first whole human genome shRNA screen using a novel avian embryo intravital...
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Spring 2011
Unsatisfactory performance of a control system may have different root causes, of which diagnosis and control have been subjects of interest. Numerous approaches have been used to identify the source of the oscillatory behavior of control systems. This work will focus on the nonlinearities...
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Fall 2019
One of the main difficulties in extending Macdonald’s theory of spherical functions from p-adic Chevalley groups to p-adic Kac-Moody groups is the absence of Haar measure in the infinite dimensional case. Related to this problem is the question of how to generalize the integral defining...