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Spring 2017

Hassanpourfard, Mahtab

One of the central puzzles concerning the interaction of low Reynolds number (Re<<1) fluid transport with bacterial biomass is the formation of filamentous structures called bacterial streamer. Bacterial streamers can be tethered at one or both ends to solid surfaces, while the rest of the...

Fall 2010

Olson, Steven

Electro-transmittance of molecular junctions was characterized electrically and studied optically at 410nm and 532nm. Between 1kHz and 100kHz there was no qualitative difference between the control samples and the molecular junction samples, however there were difficulties with reproducibility of...

Spring 2014

Martinez-Quijada, Jose

The lab-on-chip (LOC) technology could transform and greatly enhance the health care system by making genetic diagnosis tests fast, accurate and readily accessible. However, most LOC systems are not prepared to resist variations of their external environment, as they depend upon many...

Spring 2022

Menze, Lukas

The rapid isolation of specific rare target cells is of rising importance in current targeted patient treatment plans. Common cell sorting approaches such as stream-based dielectrophoresis (DEP) based cell sorters are limited by their spatial dimensions as only a number of cell types...

Spring 2014

Reynolds, Matthew

Lab-on-chip systems will be a major component in the future of health care. These technologies enable point-of-care testing by miniaturizing and improving the efficiency of many diagnostic techniques. Possible applications include the detection of various pathogens using genetic amplification...

Fall 2013

Ha, Debbie Feng Shan

Conventional cytometry uses fluorescently labelled cells that are laborious and costly to prepare. Using a label-free technique, individual cells can be differentiated by light scattering patterns, a result of different physical attributes. This thesis describes the development of a microfluidic...

Spring 2014

Gunda, Naga Siva Kumar

The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...

Spring 2011

Nazemifard, Neda

This dissertation investigates the size based separation of DNA molecules in nanoparticle arrays under asymmetric pulsed electrophoresis. Crystalline arrays of nanoparticles within microfluidic channels are fabricated using colloidal self-assembly, yielding structures with pore sizes ranging from...

Fall 2012

Malekpourkoupaei, Ali

Clinical point-of-care (POC) diagnosis remains an open and challenging field of research worldwide in which the study of the mechanism and dynamics of protein molecule separation using electrophoresis is of considerable interest. The quality of a protein separation is strongly dependent on the...

Fall 2014

Zhang, Le

We demonstrate the functionalization of a highly ordered porous molecular sieving matrix created by colloidal self-assembly (CSA) of 2 micrometer diameter silica particles in microfluidic chips, for highly efficient immuno-capture of viruses. By tuning the particle size, with appropriate surface...