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Development of KMPR-Based Microfluidic Structures for Use in LOC Systems

  • Author / Creator
    Reynolds, Matthew
  • Lab-on-chip systems will be a major component in the future of health care. These technologies enable point-of-care testing by miniaturizing and improving the efficiency of many diagnostic techniques. Possible applications include the detection of various pathogens using genetic amplification and analysis techniques. Ideally, a system should provide rapid sample-in-answer-out capabilities without requiring a patient to leave their own home. The goal of this thesis is to advance lab-on-chip manufacturing technologies by using the epoxy-based photopolymer KMPR with the eventual goal of integrating lab-on-chip devices with CMOS technology. In order to produce integrated microfluidics using this material the physical properties of KMPR and the effect of changing processing conditions on those properties was studied. Following this devices were developed consisting of polymeric microfluidic structures (channels, wells and chambers) and integrated metal thin film structures such as heaters and electrodes. Validation of the fabricated devices was performed in order to confirm their operation.

  • Subjects / Keywords
  • Graduation date
    2014-06
  • Type of Item
    Thesis
  • Degree
    Master of Science
  • DOI
    https://doi.org/10.7939/R3C10M
  • License
    This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.
  • Language
    English
  • Institution
    University of Alberta
  • Degree level
    Master's
  • Department
    • Department of Electrical and Computer Engineering
  • Specialization
    • Biomedical Engineering
  • Supervisor / co-supervisor and their department(s)
    • Elliott, Duncan (Department of Electrical and Computer Engineering)
    • Sameoto, Dan (Department of Mechanical Engineering)
    • Backhouse, Chris (Department of Electrical and Computer Engineering, University of Waterloo)
  • Examining committee members and their departments
    • Sit, Jeremy (Department of Electrical and Computer Engineering)
    • Elias, Anastasia (Department of Chemical and Materials Engineering)