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Skip to Search Results- 1Baron, Corey A
- 1De, Ashmita
- 1Holinski, Bradley J
- 1Larmour, Sarah
- 1Little, Graham Taylor
- 1Meadus, William Q
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Quantitative Susceptibility Mapping in Human Brain: Short Echo Timing, Thin Slab, and Non-harmonized Multisite Applications
DownloadSpring 2023
Quantifying tissue magnetic susceptibility provides a non-invasive way to monitor iron and myelin abnormalities associated with several neurodegenerative diseases. Quantitative susceptibility mapping (QSM) is a post-processing technique that retrieves the susceptibility distribution from the...
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Advances in Quantitative Susceptibility Mapping for Human Brain: Applications in Hemorrhage, Motion, Blood Vessels
DownloadFall 2022
Quantitative Susceptibility Mapping (QSM) is an emerging postprocessing method, computed from phase images, which is finding wide application in quantifying iron content in healthy and pathological tissue. However, QSM is still not commonly used in clinical practice. This thesis discusses the...
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Fall 2022
Multiple Sclerosis (MS) is a chronic neurodegenerative disease which is mainly characterized by inflammation, demyelination, and axonal loss. Conventional Magnetic Resonance Imaging (MRI) has become the most established imaging tool in the diagnosis and follow-up of MS in clinical practice....
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Fall 2021
Tracking myelination and demyelination in the brain is a crucial part of studies on neurodegenerative diseases such as Multiple Sclerosis (MS). Classic MRI techniques are unable to provide enough information about the pathology of tracts and lesions. Multi-component analysis of multi-echo data...
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Spring 2020
Pulmonary edema (PE) involves an excess of extravascular lung water (EVLW) due to an imbalance in fluid filtration which results in hypoxia and respiratory distress. Cardiogenic pulmonary edema is a primary clinical feature and therapeutic target in acute heart failure. Current methods in...
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Magnetic Resonance Imaging of the Brain in Prenatal Alcohol Exposure and Advances in Measuring Cortical Microstructure
DownloadFall 2020
Fetal alcohol spectrum disorder (FASD) encompasses a large spectrum of physical, cognitive and behavioral deficits resulting from prenatal alcohol exposure. Studies using magnetic resonance imaging (MRI) have shown structural and functional brain alterations in children and adolescents with...
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Oscillating Gradient Spin Echo (OGSE): A Study of Short Diffusion Time Effects in Human Brain at 3T
DownloadSpring 2020
Diffusion-weighted magnetic resonance imaging (DWI) is a non-invasive MRI technique that is sensitive to the diffusion of water molecules within the body. Its ability to encode water displacements enables it to detect changes in neural microstructure, such as those due to normal healthy aging or...
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Quantitative Susceptibility Mapping in Ischemic Stroke: Cerebral Veins, Tissue, and Microbleeds
DownloadSpring 2019
Quantitative susceptibility mapping (QSM) is an emerging magnetic resonance imaging (MRI) post-processing technique that uses phase images from a gradient echo sequence to create magnetic susceptibility maps. QSM is sensitive to paramagnetic iron found in various states of blood, from...
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Fall 2016
Arterial spin labeling (ASL) is a magnetic resonance imaging (MRI) noninvasive method, capable of measuring perfusion, i.e. blood flow, with blood as an intrinsic contrast. ASL measurements of cerebral perfusion are usually acquired at very low spatial resolution (> 60mm3 voxels), for several...
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Fall 2015
Fats are a fundamental building block of the human body, but accumulation of unwanted fat in and around tissues is a common pathology related to many disease mechanisms. Magnetic Resonance Imaging (MRI) offers a host of methods to differentiate water and fat signals in images or spectra, for...