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Skip to Search Results- 4Goodman, K.J.
- 3Chakrabarti, Subhadeep
- 3Field, Catherine J.
- 3Geary, J.
- 3Proctor, Spencer D.
- 3Wu, Jianping
- 84Graduate and Postdoctoral Studies (GPS), Faculty of
- 84Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 19Agricultural, Food and Nutritional Science, Department of
- 19Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 4CANHelp Working Group
- 4CANHelp Working Group/Journal Articles (CANHelp Working Group)
- 10Department of Agricultural, Food, and Nutritional Science
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- 8Department of Medicine
- 4Centre for Neuroscience
- 4Faculty of Rehabilitation Medicine
- 3Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 2Jamali, Fakhreddin (Faculty of Pharmacy and Pharmaceutical Sciences)
- 2Kerr, Bradley (Anesthesiology and Pain Medicine)
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Fall 2009
There is substantial evidence of the elevated risk of cancer among individuals with type 2 diabetes. Very little is known, however, about the role that antidiabetic therapies play in this relationship. The objective of this program of research was to examine whether there is a therapeutic risk...
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Application of ROC curve analysis to metabolomics data sets for the detection of cancer in a mouse model
DownloadFall 2010
The goal of this study was to show that quantifiable metabolic changes may be used to screen for cancer. NIH III nude mice (n=22) were injected with human GBM cells, with daily urine samples collected pre and post-injection. 14 mice were injected with saline to serve as controls. The...
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2016
Chakrabarti, Subhadeep, Wu, Jianping
Cardiovascular diseases (CVD) such as myocardial infarction and stroke are a major cause of morbidity and mortality worldwide. Impairment of the normal vasorelaxant functions of the vascular endothelium, termed endothelial dysfunction; appear to underlie the pathogenesis of CVD. Endothelial...
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Fall 2010
Abstract: Introduction: Partial bladder outlet obstruction (pBOO) is a ubiquitous problem that results in renal damage. We hypothesize that change in the bladder progresses over time. Methods: Fischer rats underwent surgical pBOO for 2, 4, 8, or 13 weeks and were compared to shams. Urodynamic...
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Fall 2018
Background: Cancer-associated venous thromboembolism (VTE) is associated with significant morbidity and mortality. Cancer patients are at higher risk of VTE recurrence despite anticoagulation and bleeding complications while on anticoagulation. There are some risk factors of bleeding specific...
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2011
Boutin, Hervé, Crossman, David, Smigova, Alison, Drake, Caroline, Allan, Stuart M., Francis, Sheila, Gerhard, Alexander, Jones, Matthew S., Hinz, Rainer, Kassiou, Michael, Hopkins, Stephen J., Vail, Andy, Herholz, Karl, Tyrrell, Pippa J., Selvarajah, Johann R., Rothwell, Nancy J., Julyan, Peter, Georgiou, Rachel F., Brown, Gavin, Maroy, Renaud, Denes, Adam, Russell, James C., Proctor, Spencer D., McColl, Barry W., Prenant, Christian, Hulme, Sharon
Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in humans. The hypothesis that systemic inflammation may induce brain...
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Butyrate-mediated genomic changes involved in the non-specific host defenses, matrix remodelling and the immune response in the rumen epithelium of cows afflicted with subacute ruminal acidosis
Download2013
Steele, Michael A., Greenwood, Sabrina L., Plaizier, Jan C., McBride, Brian W., Matthews, James C., Laarman, Anne H., AlZahal, Ousama, Dionissopoulos, Louis
Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by...
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2008-12-01
Kelly, Janet, Lanier, Anne, Santos, Maria, Healey, Sylvia, Louchini, Rabia, Friborg, Jeppe, Young, T. Kue
"Objectives: This is first of 2 papers on the Circumpolar Inuit Cancer Review, an international collaborative effort involving researchers and health officials from Alaska, Canada and Greenland. It covers the period 1989–2003, updating the last review (1969-1988) and together provides an overview...
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2008-12-01
Kelly, Janet, Lanier, Anne, Santos, Maria, Healey, Sylvia, Louchini, Rabia, Friborg, Jeppe, Young, T. Kue
"Objectives: This is the second of 2 papers reporting on the result of the Circumpolar Inuit Cancer Review, an international collaborative effort involving researchers and health officials from Alaska, Canada and Greenland. Methods: Inuit cancer cases by age-sex group and anatomic site were...