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Skip to Search Results- 11Statistical analysis
- 8Vitrification
- 6Porcine
- 5Articular cartilage
- 5Cryopreservation
- 5Digital humanities
- 8Chemical and Materials Engineering, Department of
- 8Chemical and Materials Engineering, Department of/Research Articles and Materials (Chemical and Materials Engineering)
- 8Graduate and Postdoctoral Studies (GPS), Faculty of
- 8Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 7Surgery, Department of
- 7Surgery, Department of/Orthopaedic Surgery
- 1Adesida, Adetola B (Surgery)
- 1Dr. Michael Dyck (Department of Agricultural, Food, and Nutritional Science)
- 1Elliott, Janet A W (Chemicals and Material Engineering)
- 1Gina R. Rayat (Surgery)
- 1Henein, Hani (Department of Chemical and Materials Engineering)
- 1Ivey, Douglas (Department of Chemical and Materials Engineering)
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2013
Yu, H., Jomha, N. M., Elliott, J. A., Al-Abbasi, K. K., McGann, L. E.
In previous research, we successfully cryopreserved intact human articular cartilage on its bone base with high chondrocyte viability using a vitrification protocol that entailed sequential exposure to several cryopreserving agents (CPAs) at lowering temperatures resulting in a high final...
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Computational support systems for prediction and characterization of protein crystallization outcomes
DownloadFall 2013
Analysis of protein structures may reveal their function, regulation and interactions. Almost 90% of the known protein structures were solved using X-ray crystallography; however, many more structures remain unsolved. Protein Structure Initiative (PSI) project was created to speed up structure...
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2010
Law, G. K., Elliott, J. A., Forbes, J. F., Weiss, A. D., McGann, L. E., Jomha, N. M.
Large articular cartilage defects have proven difficult to treat and often result in osteoarthritis of the affected joint. Cryopreservation of articular cartilage can provide an increased supply of tissues for osteochondral allograft but cryoprotective agents are required; however, few studies...
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2012
Law, G. K., Forbes, J. F., Elliott, J. A., McGann, L. E., Jomha, N. M., Prasad, V., Almansoori, K. A.
Background Vitrification is a method of cryopreservation by which cells and tissues can be preserved at low temperatures using cryoprotective agents (CPAs) at high concentrations (typically ⩾6.0 M) to limit the harmful effects of ice crystals that can form during cooling processes. However, at...
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Determination of Cryoprotectant Behavior, Physiological and Anatomical Characterization of the Porcine Meniscus as a Model for Future Meniscal Vitrification Studies
DownloadSpring 2016
The menisci hold significant, protective biomechanical function in the human knee and loss of meniscal functions have been linked to the development of osteoarthritis. Currently, irreparable or non-salvageable meniscal injuries undergo partial or total removal of injured menisci to alleviate...
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Fall 2011
Metabolomics aims to study all small-molecule compounds (i.e. metabolites) in cells, tissues, or biofluids. These compounds provide a functional readout of the physiological, developmental, and pathological state of a biological system. The field of metabolomics has expanded rapidly over the last...
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2014
Prasad, V., Laouar, L., Jomha, N. M., McGann, L. E., Fahmy, M. D., Almansoori, K. A., Elliott, J. A.
Vitrification of articular cartilage (AC) could enhance tissue availability but requires high concentrations of cyroprotective agents (CPAs). This study investigated relative injuries caused by commonly used CPAs. We hypothesized that the in situ chondrocyte dose–injury relationships of five...
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Finite Element Model of the Thermal Profile During Submerged Arc Welding with One and Two Electrodes
DownloadFall 2016
The submerged-arc welding (SAW) process is used extensively in the manufacturing of pipes. The heat flow introduced by the welding operation has a significant impact on the properties of both the weld metal and the heat affected zone (HAZ). The work presented in this thesis aims to develop a...
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1988
Plastow, G. S., Mileham, A. J., Siggens, K. W.
A 3.8 kb male specific fragment was observed following agarose gel etectrophoresis of porcine DNA digested with Sph I. DNA was recovered from this region of a gel using DE-81 paper and ligated to Sph I digested pUC18. Plasmids carrying male specific sequences were identified by their differential...