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Skip to Search Results- 1Abou Zeinab, Rami M
- 1Abuetabh, Yasser H
- 1Al Yousef, Habib Saleh M
- 1Albahrani, Redha Mohammed
- 1Allen,Richelle J
- 1Almizraq, Ruqayyah J
- 26Medical Sciences-Laboratory Medicine and Pathology
- 25Medical Sciences- Laboratory Medicine and Pathology
- 5Medical Sciences - Laboratory Medicine and Pathology
- 1Chemical and Materials Engineering and Medical Sciences - Laboratory Medicine and Pathology
- 1Medical Science - Laboratory Medicine and Pathology
- 1Medical Sciences – Laboratory Medicine and Pathology
- 5Li, Xing-Fang (Laboratory Medicine and Pathology)
- 4Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 4Lai, Raymond (Laboratory Medicine and Pathology)
- 3Acker, Jason (Laboratory Medicine and Pathology)
- 3Le, X. Chris (Laboratory Medicine and Pathology)
- 3Leng, Roger (Laboratory Medicine and Pathology)
Results for "departments_tesim:"Medical Sciences- Laboratory Medicine and Pathology""
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Analytical and Toxicological Characterization of Novel Nitrogen Containing Disinfection Byproducts
DownloadFall 2012
Disinfection byproducts (DBPs) are an unwanted consequence of water disinfection. Consumption of chlorinated drinking water has been associated with an increased risk of bladder cancer; however, the DBP or DBPs responsible has not been identified. The N-nitrosamines are a class of DBPs that are...
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Analytical Characterization of Halobenzoquinones as Emerging Disinfection Byproducts in Disinfected Water
DownloadSpring 2016
Water disinfection is necessary for killing pathogens, but it causes an unintended chemical risk from the formation of disinfection byproducts (DBPs). Epidemiological studies show a potential association of water disinfection with increased risk of bladder cancer. It is unknown what DBPs are...
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Spring 2016
There is evidence that the symptoms associated with sickle cell disease can be relieved by using plant extracts containing anthocyanin (AC) agents. It has been established that ACs were able to reverse sickle cell morphology to a biconcave disc shape. However, no specific form of AC has been...
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Association mapping of genes using whole genome polymorphism arrays: Identification of markers of breast cancer susceptibility in Alberta women
DownloadFall 2010
Chakravarthy Sridharan, Malinee
Breast cancer is a heterogeneous, polygenic disease and is influenced by genetic, environmental and life-style factors. Many single nucleotide polymorphisms (SNPs) associated with breast cancer risk have been identified in genome-wide association studies (GWASs) by several research groups for...
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Fall 2009
First-line treatment of breast and other cancers with Taxol is compromised by resistance in up to 40% of patients. To improve chemotherapy, it is vital to understand how Taxol resistance develops and to overcome this. Autotaxin (ATX) promotes cancer cell survival, growth, migration, invasion...
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Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic Species
DownloadFall 2013
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
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Fall 2009
Recent advances in the fundamental theories in cryobiology using thermodynamic principles have created new opportunities for innovative methodologies in cryobiology. This thesis tested the hypothesis that calculated indicators of the two-factor hypothesis of cryoinjury, depending on cellular...
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Characterization of Norovirus strains and a seroprevalence study to understand the fluctuation of outbreak activity in Alberta, Canada
DownloadFall 2016
Norovirus (NoV) is recognized as the leading agent causing gastroenteritis among individuals of all ages. Historical data of NoV outbreak surveillance in Alberta, Canada, from the period July 2000 to June 2008 demonstrated a biennial pattern of NoV outbreak activity, in which peaks of high...
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Characterization of Phosphoglycerate Kinase Expressed on the Surface of Group B Streptococcus
DownloadSpring 2012
Group B streptococcus (GBS) is a major cause of invasive disease in the neonatal and adult populations. To mediate invasive disease, GBS encodes a variety of surface expressed and secreted components. One surface expressed protein that may contribute to GBS virulence is phosphoglycerate kinase...