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- 8Biological Sciences, Department of/Journal Articles (Biological Sciences)
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- 3Biochemistry, Department of/Journal Articles (Biochemistry)
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- 2Chemistry, Department of/Journal Articles (Chemistry)
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Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation and anaphase entry
Download2012
Campbell, S.D., Homola, E.M., Fasulo, B., Yu, K.R., Hsieh, T.S., Sullivan, W., Koyama, C.
Defects in DNA replication and chromosome condensation are common phenotypes in cancer cells. A link between replication and condensation has been established, but little is known about the role of checkpoints in monitoring chromosome condensation. We investigate this function by live analysis,...
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1990
Many autecological effects of temperature on fish are known, and fishery biologists have begun to incorporate this knowledge into population-level relations that can be used to assess possible effects of climatic warming on fishes and their habitats. However, the problem of extrapolating these or...
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2010
Lindgren, Johan, Konishi, Takuya, Chiappe, Luis M., Caldwell, Michael W.
Mosasaurs (family Mosasauridae) are a diverse group of secondarily aquatic lizards that radiated into marine environments during the Late Cretaceous (98–65 million years ago). For the most part, they have been considered to be simple anguilliform swimmers – i.e., their propulsive force was...
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Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22
2013
Pfrengle, F., Kawasaki, N., Paulson, J. C. , Macauley, M. S.
Differentiation of self from nonself is indispensable for maintaining B cell tolerance in peripheral tissues. CD22 and Siglec-G (sialic acid-binding Ig-like lectin G) are two inhibitory coreceptors of the BCR that are implicated in maintenance of tolerance to self Ags. Enforced ligation of CD22...
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Density-Dependent Effects and the Regulation of Crucian Carp Populations in Single-Species Ponds
Download1994
Tonn, W. M., Holopainen, I. J., Paszkowski, C. A.
Crucian carp (Carassius carassius) is often the only fish species present in small ponds of northern Europe. Such populations are typically at high densities and consist primarily of small, relatively slender, and short-lived fish; populations in multispecies assemblages in lakes display opposite...
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Enhancing productive capacity in the Canadian Arctic: Assessing the effectiveness of instream habitat structures in habitat compensation
Download2004
We examined the effectiveness of physical habitat structures (ramps, V-weirs, vanes, and groins) at increasing the productive capacity of a newly created 3.4-km artificial stream in the Barrenlands region of the Northwest Territories, Canada. We quantified changes in fish density and growth in...
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Goldfish ghrelin: Molecular characterization of the complementary deoxyribonucleic acid, partial gene structure and evidence for its stimulatory role in food intake
Download2002
Rivier, J., Kaiya, H., Lin, X.W., Cervini, L., Unniappan, S., Peter, R.E., Kangawa, K.
Complementary deoxyribonucleic acid (cDNA) encoding goldfish preproghrelin was identified using rapid amplification of the cDNA ends (RACE) and reverse transcription (RT)-polymerase chain reaction (PCR). The 490 bp cDNA encodes a 103 amino acid preproghrelin which has a 26 amino acid signal...
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1998
Rask, M., Tonn, W. M., Toivonen, J., Magnuson, J. J., Banerjee, A., Sanchez, O.
To evaluate the roles of extinction and isolation in predicting richness and composition of fish assemblages in small forest lakes of Finland and Wisconsin, we analyzed data from 114 Finnish and 55 Wisconsin lakes 0.2-86.9 ha in area. Six isolation variables characterized properties of stream...
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Oxidative stress mediates estrogen receptor independent killing and contributes to tamoxifen resistance
Download2016
Godbout, Roseline, Brindley, David N., McMullen, Todd, Mackey, John R., Benesch, Matthew, Mi, Si, Venkatraman, Ganesh, Liu, Rong-Zong, Curtis, Jonathan M., Tang, Xiaoyun, Bekele, Raie T.
Tamoxifen is the accepted therapy for patients with estrogen receptor-α (ERα)-positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases. To improve breast cancer treatment it is vital...
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Regulation of Na+/H+ Exchanger Gene Expression: Role of a poly T rich region in regulation of expression of the NHE1 promoter
Download1996-01-01
Yang, Weidong, Wang, Huayan, Fliegel, Larry
In this study we examine regulation of expression of the Na+/H+ exchanger promoter in L6 and NIH 3T3 cells. We have identified a highly conserved poly(dA·dT)-rich region that appears to be important in regulation of expression of the NHE1 gene. Deletion or mutation of this region results in...