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Skip to Search Results- 28Stroke
- 21Spinal cord injury
- 8Plasticity
- 6Rehabilitation
- 5Walking
- 4Functional electrical stimulation
- 1Alvarado, Laura
- 1Anderson, Sharon
- 1Anderson, Sharon D
- 1Arvanitidis, Anastasia P
- 1Auriat, Angela Michelle
- 1Bamford, Jeremy, Andrew
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Investigation of intermittent electrical stimulation as a potential prophylaxis against the formation of deep pressure ulcers after spinal cord injury
DownloadFall 2009
Deep tissue injury (DTI) is a severe form of pressure ulcers resulting from ischemia and mechanical damage due to unrelieved pressure. Despite many preventative methods, none so far has significantly reduced the incidence of DTI. The use of a novel method of pressure ulcer prevention,...
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Spring 2019
Walking is a locomotor task that integrates information from all over the nervous system. The lumbosacral spinal cord houses neural networks that contribute to locomotion. These networks dominate locomotor activity during development and may provide suitable targets for restoring function after...
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Fall 2021
Spinal cord injury (SCI) not only leads to motor and sensory dysfunction, but just as debilitating are secondary consequences of SCI such as bowel disorders, neuroinflammation, immune suppression, pain and psychiatric disorders. In this thesis, I explore multiple aspects of recovery after SCI in...
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Spring 2014
Bleeding within the brain parenchyma causes a severe form of stroke named intracerebral hemorrhagic stroke (ICH). An understanding of how brain injury occurs after an ICH may suggest alternative therapies. For this reason, the current dissertation focuses on two important questions of how the...
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Fall 2012
Reading impairment, known as alexia, frequently co-occurs with damage to the language areas of the brain in aphasia. Text-based reading treatments have been shown to improve reading fluency, but the mechanisms behind such improvement remain unclear. This study investigates the efficacy of...
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MODELING INCOMPLETE CERVICAL SPINAL CORD INJURY IN RATS TO EXPLORE MECHANISMS OF REHABILITATIVE TRAINING
DownloadFall 2013
Although limited functional recovery is observed following spinal cord injury (SCI), the most successful approach to promote recovery to date has been rehabilitative training. However, the effects of training are not stunning. With a thorough understanding of the intracellular mechanisms involved...
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Motor unit recruitment by intraspinal microstimulation and long-term neuromuscular adaptations
DownloadFall 2009
Spinal cord injury is a devastating neurological disorder partially characterized by a loss of motor function below the lesion. The dramatic loss of activity results in muscle atrophy and slow-to-fast transformation of contractile elements, producing smaller, weaker and more fatiguable muscles....
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Spring 2018
Background: Stroke is a leading cause of adult disability globally. In Canada, about 405,000 individuals are living with the effects of stroke and this number is projected to rise by over 60% in the next two decades. People with stroke are often physically inactive and sedentary which may...
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Neuronal Mechanisms of Hyperexcitability in Individuals with Spasticity after Spinal Cord Injury and Individuals with Bruxism
DownloadFall 2013
Motoneuron hyperexcitability is a characteristic of several different motor disorders. We examined neuronal mechanisms of hyperexcitability in two of these disorders: spasticity after spinal cord injury (SCI) and bruxism. Involuntary muscle spasms after SCI occur as a result of uncontrolled...
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Fall 2023
The overarching idea of this thesis stemmed from previous work in our lab, where it was noticed that females and males exhibited different disease trajectories in a model of Multiple Sclerosis. Combined with our observation of different outcome metrics for peripheral nociception suggested that...