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2007

Guan, L., Guo, Y., Liu, T., Li, H., Wang, J., Zheng, W.M., Wong, G.K.

Background The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for intra-species alignments, among which are successful ones with high specificity and speed. The other group contains more...

2012

Xia, Y., Zhang, X., Mu, Z., Li, X., Wang, T., Qu, J., Chen, H., Li, K., Zhu, L., Wang, L., Liu, Y., Zhang, K., Guan, J., Wu, H., Jiang, A., Yin, G., Xi, D., Shuai, S., Lang, Q., Jiang, Y., Wang, Z., Luo, Z., Xiao, H., Li, Y., Huang, S., Gu, Y., Beck, S., Ma, J., Wang, H., Jing, L., Plastow, G. S., Jiang, Z., Gao, X., Chen, L., Tang, G., Wang, J., Li,R., Li, M., Mai, M., Wang, Y., Wang, X., Zhong, Z., Nie, J., Zhou, S., Yang, H., Yi, N., Li, N.

It is evident that epigenetic factors, especially DNA methylation, have essential roles in obesity development. Here, using pig as a model, we investigate the systematic association between DNA methylation and obesity. We sample eight variant adipose and two distinct skeletal muscle tissues from...

2004

Wang, J., Chen, Y., Zhao, H., Dai, M., Zhao, W., Huang, X., Zhang, Y., Ren. X., Jiao, Y., Wong, G., Wei, S., Ni, P., Yu, J., Zhang, J., Li, S., Yang, H., Fu, J., He, X.

Rice is a major food staple for the world's population and serves as a model species in cereal genome research. The Beijing Genomics Institute (BGI) has long been devoting itself to sequencing, information analysis and biological research of the rice and other crop genomes. In order to facilitate...

2017-01-06

Bording-Jorgensen, M. , O'keefe, S. , Mason, A., Warren, K., Patterson J., Jovel, J., Wong, G., Wang, W.

Multiple sclerosis (MS) is a common cause of non-traumatic neurologic disability with high incidence in many developed countries. Although the etiology of the disease remains elusive, it is thought to entail genetic and environmental causes, and microbial pathogens have also been envisioned as...

2011

Black, T.A., Izaurralde, R.C., Lokupitiya, E., Munger, J.W., Schaefer, K., Weng, E., Richardson, A.D., Altaf Arain, M., Luo, Y., Ciais, P., Ricciuto, D.M., Stoy, P.C., Dietze, M.C., Poulter, B., Barr, A.G., Liu, S., Hollinger, D., Tian, H., Suyker, A.E., Verbeeck, H., Price, D.T., Grant, R.F., Peng, C., Baker, I.T., Vargas, R., Anderson, R.S., Tonitto, C., Sahoo, A.K., Chen, J.M., Flanagan, L.B., Riley, W.J., Wang, W., Lafleur, P., Gough, C.M., Verma, S.B., Kucharik, C.J.

Ecosystem models are important tools for diagnosing the carbon cycle and projecting its behavior across space and time. Despite the fact that ecosystems respond to drivers at multiple time scales, most assessments of model performance do not discriminate different time scales. Spectral methods,...

2005

Li, S., Dai, M., He, X., Zhang, Y., Ruan, J., Burt, D., Yu, J., Wang, J., Yang, H., Hu, Y., Liu, B., Wong, G., Ye, C., Chen, J., Cong, L., Fang, L.

Working in parallel with the efforts to sequence the chicken (Gallus gallus) genome, the Beijing Genomics Institute led an international team of scientists from China, USA, UK, Sweden, The Netherlands and Germany to map extensive DNA sequence variation throughout the chicken genome by sampling...

2009

Tsuneda, I., Wang, W., Currah, R.S., Tsuneda, A.

The host-endophyte interaction between roots of aspen (Populus tremuloides) andCryptosporiopsis radicicola was examined primarily by transmission electron microscopy. Hyphae growing on the exterior of the inoculated roots had a thick, electron-dense, adhesive sheath. At hyphal contact and...

2008

Li, R., Wang, J., Wong, G.K.S., Zheng, H., Xu, S., Clark, T., Zheng, X., Vang, S.

Background Gene conversion causes a non-reciprocal transfer of genetic information between similar sequences. Gene conversion can both homogenize genes and recruit point mutations thereby shaping the evolution of multigene families. In the rice genome, the large number of duplicated genes...

2006

Wang, W., Li, J., Liu, D., Lu, Z., Zheng, H., Wong, G., Cai, Z., Fan, C., Zhang, J., Vang, S., Long, M., Zhang, G., Wang, J., Shi, J.

Retroposition is widely found to play essential roles in origination of new mammalian and other animal genes. However, the scarcity of retrogenes in plants has led to the assumption that plant genomes rarely evolve new gene duplicates by retroposition, despite abundant retrotransposons in plants...

2007

Wang, W., Wang, H., Wong, G.K.S., Zheng, H., Clark, T., Zhang, G., Kang, L., Wang, J., Shi, J., Wang, X.

Background Insects constitute the vast majority of known species with their importance including biodiversity, agricultural, and human health concerns. It is likely that the successful adaptation of the Insecta clade depends on specific components in its proteome that give rise to specialized...