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Fall 2019
Introduction: Congenital Diaphragmatic Hernia (CDH), is a birth defect that occurs in approximately 1 in every 3,000 births. It arises when the diaphragm fails to form properly during development leaving a hole in the muscle. In utero, the abdominal contents protrude through hole, taking up...
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Spring 2024
Introduction: Vitamin A is an essential dietary micronutrient and its active metabolite all-trans retinoic acid is a key regulator of both hepatic retinoid and hepatic lipid homeostasis. Retinoic acid is a potent transcriptional regulator with more than 500 proposed target genes, however the...
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Vitamin D Status and Health-care Outcomes in an Ambulatory Population of Patients with Diabetes and Chronic Kidney disease: A Five-year Follow-up.
DownloadSpring 2018
Vitamin D (VitD) deficiency is a prevalent condition in Canada, especially in northern latitudes where sunlight exposure is limited. Elderly patients especially those with chronic conditions such as Diabetes Mellitus (DM) and Chronic Kidney Disease (CKD) have a higher risk of developing vitD...
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Vitamin D Status and Markers of Cardiometabolic and Liver Disease Risk in Childhood Obesity
DownloadSpring 2017
Vitamin D insufficiency is highly prevalent in children (up to 40%), particularly in northern climates such as Alberta, due to reduced sunlight exposure and low intake. Although suboptimal vitamin D status and metabolic dysregulation are commonly observed in obesity, little is known about the...
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Vitamin D Supplementation and Bone Health in Adults with Diabetic Nephropathy: Preliminary Findings from a Randomized Controlled Trial
DownloadFall 2013
Vitamin D (vitD) is a nutrient of concern in Canada particularly for those with diabetes and chronic kidney disease (CKD). Participants (18-80y) with diabetes and CKD were randomized to receive either 50mcg/day (n=33) or 1,000mcg/month (n=30) vitD3 for 6-months. Variables studied included:...
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Vitamin D supplementation and bone health in adults with diabetic nephropathy: The protocol for a randomised controlled trial
Download2014
Hoffmann, Michelle R., Jindal, Kailash, Senior, Peter A., Mager, Diana R., Jackson, Stephanie T.
Background Suboptimal vitamin D status is highly prevalent in Northern communities, particularly in those patients with chronic diseases such as diabetes and chronic renal disease. Emerging literature suggests that adherence to daily vitamin D supplementation may be an important factor...