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- 2Li, Leo
- 2Nizio, Katie D
- 1Abdel Latif Ibraheem, Ahmed Abdel Mohsen
- 1Abdelfattah, Ahmed
- 1Abel, Robin Jacob
- 1Abou-Ghanem, Maya
- 23Organic compounds. Synthesis.
- 21Capillary electrophoresis.
- 18Chemical reactions.
Stimuli-Responsive Microgel-Based Materials and Their Assembly for Controlled Drug Delivery and Sensing SystemsDownload
Conventional drug delivery methods result in a burst of drug concentration in plasma, followed by a decline, which leads to issues with maintaining drug concentrations in the therapeutic range. Furthermore, this high plasma concentration can lead to undesirable (and dangerous) side effects that...
Interfacing Silicon-Based Quantum Dots with Proteins for Biological and Sensing ApplicationsDownload
This dissertation presents the preparation of functional bioinorganic hybrids from silicon-based quantum dots (SiQDs) and enzymes and the use of SiQDs and green fluorescent protein as ratiometric photoluminescent sensors for nerve agents. Chapter 2 discusses the preparation of water-soluble...
Developing diverse effective synthetic tools to generate structural complexity in molecular frameworks is considered an attractive area of pursuit. Among those tools, the Nazarov reaction is an effective route towards the generation of complex polycyclic skeletons like five-membered rings, which...
The development of life sciences has imposed higher requirements for biochemical analysis, especially for point-of-care analysis. Polymer-made centrifugal CD microfluidic chips could fulfill the needs of biochemical analysis with their low cost, the feasibility of mass production, excellent...
Theoretical understanding and method development for high performance liquid chromatography-mass spectrometry for environmental analysisDownload
Method development is a fundamental key step for effective and efficient analytical separations and analyses. Of particular importance is method development for high performance liquid chromatography-mass spectrometry (HPLC-MS). Specifically, environmental analysis applications require dedicated...
Carbon-on-Gold Films and Spontaneous Adsorption of Aryldiazonium Salts for Surface Plasmon Resonance SensingDownload
Over the past decades, surface plasmon resonance (SPR) technology has gained popularity as a powerful analytical technique for the study of biomolecular interactions and medical diagnostics. This is made possible thanks to the well-established gold-thiolate chemistry. However, the limited...
Investigation of banglenes as neurotrophic agents and development of a new fluorescent protein- based FRET pairDownload
This thesis describes efforts towards understanding the neurotrophic activity of banglenes and the development of a new fluorescent protein-based FRET pair. Neurotrophic small molecule natural products are functional analogs of signaling proteins called neurotrophins, which cause a pro-growth,...