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- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Functionalized Thermo-responsive Polymer Core-shell Materials for use in Controlled Dye Release, Thin-film Composite Membranes, and Water Desalination
DownloadSpring 2024
This thesis focuses on the varied applications of core-shell structured stimuli- responsive polymer materials and their applications in water treatment. The relevant background and introduction to stimuli-responsive polymers, core-shell particles and morphologies, and membrane separations systems...
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New abundant 4CzIPN-derivatized Photosensitizers and Catalysts for Photosynthetic Organic Reactions and Solar Fuels
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The development of artificial photosynthetic systems is a promising strategy to meet future energy demands of our society and to reverse the impact of anthropogenic CO2 in the environment. Energy conversion devices such as photoelectrochemical cells are one key component in the transition to a...
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Mechanisms of Chiral Features of Atomically Precise Metal Clusters and Resonant Transition Metal Complexes: Insights from Vibrational Optical Activity
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My PhD thesis primarily focuses on exploring chiroptical events and to elucidate the mechanisms responsible for chiroptical signatures in various compounds. These compounds encompass several atomically precise silver and copper clusters, a europium complex, and two highly flexible monosaccharide...
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Computational Investigation of Electrical Conductivities and Magnetism of Phosphonate Metal-Organic Frameworks and Frontier Orbital Gaps, Structure, and Proton Transfer Mechanisms in Phosphonate Hydrogen-Bonded Organic Frameworks
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The study of metal-organic frameworks (MOFs) and hydrogen-bonded organic frameworks (HOFs) has gained much interest over the last decade. MOFs and HOFs are constructed through the self-assembly of organic building units and metals (in the case of MOFs), giving rise to a diverse range of...
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Investigation of bioactive natural compounds for cardiovascular diseases and daqu fermentation, and the exploration of Beauveria bassiana as a biocontrol agent for the mountain pine beetle epidemic
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Fernandez, Kleinberg Xiandrell
Peptide-based compounds are crucial components of current research and development efforts, namely in the field of pharmaceutical therapeutics. Peptides possess complex secondary structures, resulting in a wide array of functions (e.g., signalling, or cellular structural capabilities). Advances...
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Spring 2024
Bacteria employ various antimicrobial compounds to establish themselves within bacterial communities. Bacteriocins, which are ribosomally synthesized antimicrobial compounds, play a crucial role in this dynamic. This thesis focuses on strategies for purifying and identifying diverse bacteriocins...
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Spring 2024
Luminescent silicon quantum dots (SiQDs) are attractive nanoparticles due to the utilization of non-toxic and earth-abundant silicon. Despite these advantages, challenges in optimizing their optical properties, particularly broad luminescence bandwidths and photostability, persist. This thesis...
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Spring 2023
Glycosylation is one of the most abundant and diverse post-translational modifications. Glycans participate in various key biological functions and processes including immunity, cell adhesion, endocytosis, exocytosis, molecular trafficking, and signal transduction. Previous work from our lab...
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Fall 2023
Alzheimer’s disease (AD) is a common neurodegenerative dementia, and its pathological hallmarks include amyloid-β plaque and neurofibrillary tangle formation in the brain. Genome-wide association studies (GWAS) revealed that a rare single nucleotide polymorphism (SNP) in CD33 is associated with...
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Development of Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry on Quadrupole-Orbitrap Mass Spectrometers for Metabolome Analysis
DownloadFall 2023
Chemical isotope labeling liquid chromatography-mass spectrometry (CIL LC-MS) is a powerful technique in metabolomics, offering extensive coverage of the metabolome. This method involves dividing metabolites into sub-groups based on their functional groups and subjecting them to specific labeling...