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Skip to Search Results- 16Graduate and Postdoctoral Studies (GPS), Faculty of
- 16Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3WISEST Summer Research Program
- 3WISEST Summer Research Program/WISEST Research Posters
- 1St. Stephen's College
- 1St. Stephen's College/Department of Psychotherapy and Spirituality (St. Stephen's College)
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Fall 2017
This research project is borne out of an invaluable art therapy practicum experience, during which I, the student therapist, encountered a client’s acute emotionality during therapy. As a result, I expanded my academic knowledge, clinical understanding, and sense of professional identity through...
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Augmenting Plasticity and Recovery from Stroke by Modulating the Extracellular Matrix of the Central Nervous System
DownloadFall 2017
Recovery following stroke occurs almost entirely in the first weeks post injury. Moreover, the efficacy of rehabilitative training is limited beyond this narrow time frame. Sprouting of spared corticospinal tract axons in the spinal cord makes a significant contribution to sensorimotor recovery,...
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Spring 2020
Activation of α5 GABAA receptors located on nodes of primary afferents have been found to produce a long lasting tonic primary afferent depolarization in the spinal cord (tonic PAD). In particular, C fibres have been found to be especially effective in eliciting this tonic PAD. Here by activating...
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Fall 2024
This thesis presents a novel data-driven approach for identifying categoryselective regions in the human brain that are consistent across multiple participants. By leveraging a massive fMRI dataset and a multi-modal (language and image) neural network (CLIP), we trained a highly accurate...
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Spring 2010
Microglia, the resident immune cells of the central nervous system (CNS), become activated in response to danger signals given out by other cells when homeostasis has been disturbed. Microglial activation is a multifaceted phenomenon that includes numerous distinct phenotypes. The type of...
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Fall 2012
Functional Magnetic Resonance Imaging (fMRI) measures the dynamic activity of each voxel of a brain. This dissertation addresses the challenge of learning a diagnostic classifier that uses a subject’s fMRI data to distinguish subjects with neuropsychiatric disorders from healthy controls. fMRI...
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Dynamic regulation of the cellular prion protein in microglia following histamine-induced stimulation
DownloadFall 2024
Although the cellular prion protein (PrPC) has been evolutionarily conserved throughout evolution, its precise role remains elusive. Recent findings suggest that PrPC may be involved in neuroinflammation and immune responses in the brain, and its expression can be modulated through various...
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Fall 2022
Convolution Neural Networks (CNNs) have rapidly evolved since their neuroscience beginnings. These models efficiently and accurately classify images by optimizing the model’s hidden representations to these images through training. These representa- tions have been shown to resemble neural data...
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Intracortical administration of pleiotrophin in ischemic stroke: investigating functional outcomes and glial expression
DownloadSpring 2023
Ischemic stroke is the leading cause of disability and third leading cause of death in Canada, exerting a serious burden on stroke survivors, their families, and healthcare resources. Characterized by brain damage due to loss of blood flow and oxygen supply, ischemic stroke is characterized by...