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Skip to Search Results- 76Machine learning
- 19Proteins
- 5Artificial intelligence
- 4Reinforcement learning
- 3Data mining
- 3Game theory
- 2White, Martha
- 1Afaghi, Mohammad
- 1Ajallooeian, Mohammad Mahdi
- 1Akbari, Ali
- 1Akgun, Burcin
- 1Alinezhad, Haniyeh Seyed
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Spring 2016
One of the key obstacles to the effective use of mass spectrometry (MS) in high throughput metabolomics is the difficulty in interpreting measured spectra to accurately and efficiently identify metabolites. Traditional methods for automated metabolite identification compare the target MS spectrum...
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Fall 2009
The analysis of wide-angle cellular light scattering patterns is a challenging problem. Small changes to the organization, orientation, shape, and optical properties of scatterers and scattering populations can significantly alter their complex two-dimensional scattering signatures. Because of...
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Fall 2016
α-Synuclein has been implicated in the progression of Parkinson’s disease, a neurodegenerative disorder that affects millions of people worldwide. This work reports on the structural propensity and druggability of this protein using a combination of Monte Carlo, Molecular Dynamics, and Virtual...
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Computational support systems for prediction and characterization of protein crystallization outcomes
DownloadFall 2013
Analysis of protein structures may reveal their function, regulation and interactions. Almost 90% of the known protein structures were solved using X-ray crystallography; however, many more structures remain unsolved. Protein Structure Initiative (PSI) project was created to speed up structure...
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Developing and Evaluating Algorithms for Fixing Omission and Commission Errors in Structured Data
DownloadFall 2020
The use of machine learning is rapidly rising to deliver a variety of benefits in various domains. However, developing predictive systems often faces many challenges that can drastically delay model deployment. For instance, obtaining labeled training data is one of the most expensive bottlenecks...
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Development and Application of Protected Amino Acids for the Installation of Stable Post-translational Modifications Using Solid-Phase Peptide Synthesis
DownloadFall 2022
This thesis describes the synthesis of non-canonical amino acid building blocks and their use in solid-phase peptide synthesis (SPPS) to explore peptidic drug analogues based on natural products. We replaced sensitive functionalities found in the structure of naturally produced peptides with...
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Development and Applications of Mechanics- and Data-based Capacity Models for Intact/Corroded Prestressed Concrete Bridge Girders
DownloadFall 2022
Prestressed concrete (PC) highway bridges represent an integral part of the transportation network and contribute significantly to socio-economic development. However, highway bridges are susceptible to Deterioration and thus exhibit structural deficiency after years of service, especially in the...
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Development and Validation of an Automated Essay Scoring Framework by Integrating Deep Features of English Language
DownloadFall 2016
Automated scoring methods have become an important topic for the assessments of 21st century skills. Recent development in computational linguistics and natural language processing has given rise to more rational based methods for the extraction and modeling of language features. The language...
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Spring 2013
Moraes, Thania Gislaine Vasconcelos de
The effects of broiler breeder dietary energy and protein during rearing and dietary energy level of lay diets on egg composition, offspring performance and carcass yield were evaluated. Pullets were fed a diet containing high ME (2,736 kcal/kg; HEREAR), or low ME (2,528 kcal/kg; LEREAR) combined...
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Effect of Purge Gas Flow Rate and Oxygen Impurity on Heel build-up and Prediction of Heel build-up Using Machine Learning
DownloadFall 2021
Heel buildup, i.e., the accumulation of non-desorbed/non-desorbable adsorbates and their by-products on an adsorbent, during cyclic adsorption/regeneration of volatile organic compounds (VOCs) onto activated carbon decreases its adsorption capacity and lifetime. In this this study, the effect of...