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- 46Classification
- 8Metabolomics
- 5Electrospray ionization
- 4Interdisciplinarity
- 4Proteomics
- 70Graduate and Postdoctoral Studies (GPS), Faculty of
- 70Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 8Chemistry, Department of
- 8Chemistry, Department of/Journal Articles (Chemistry)
- 4Biological Sciences, Department of
- 4Biological Sciences, Department of/Journal Articles (Biological Sciences)
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2015-04-28
Any classification system should be evaluated with respect to a variety of philosophical and practical concerns. This paper explores several distinct issues: the nature of a work, the value of a statement, the contribution of information science to philosophy, the nature of hierarchy, ethical...
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Fall 2015
This study is about a series of operational acts of identification, such as interpretations, categorizations, representations, classifications, through which past materials have acquired their meaning and therefore identity. Furthermore, this meaning-making will be demonstrated always to be...
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Adolescent Idiopathic Scoliosis: Classifying, Assessing, and Monitoring using Surface Topography Asymmetry Analysis
DownloadFall 2014
The radiation dose and the associated lifetime risk of developing cancer is a problem justifying the use of surface topography (ST) as an alternative to radiographs for monitoring scoliosis. The current ST methods mainly rely on marker placement and fail to describe the 3D aspect of the scoliosis...
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Spring 2016
The simultaneous quantification of all biological molecules, from metabolites to proteins, holds the key to discovering molecular signatures that can diagnose diseases before irreversible damages have occurred in the body. Recent advances in the field of liquid chromatography coupled mass...
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Algorithms for Adolescent Idiopathic Scoliosis Classification Based on Surface Topography Analysis
DownloadSpring 2018
While the common method for diagnosing and monitoring adolescents with idiopathic scoliosis (AIS) is X-ray radiographs from which a Cobb angle is measured, studies have shown that high radiation exposure is linked to high risk of cancer, particularly, for children and women. This thesis describes...
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Spring 2013
Each individual chromatogram is typically very sparse, especially when coupled with a technique such as mass spectrometry. Only a small portion of the recorded data actually contains potentially useful information. Since the inclusion of irrelevant information will have detrimental effects upon...
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Analytical and Toxicological Characterization of Novel Nitrogen Containing Disinfection Byproducts
DownloadFall 2012
Disinfection byproducts (DBPs) are an unwanted consequence of water disinfection. Consumption of chlorinated drinking water has been associated with an increased risk of bladder cancer; however, the DBP or DBPs responsible has not been identified. The N-nitrosamines are a class of DBPs that are...
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Application of Electrospray Ionization Mass Spectrometry to Study Protein-Ligand Interactions and Enzyme Kinetics
DownloadFall 2015
This thesis describes the development and application of electrospray ionization mass spectrometry (ESI-MS) to study the noncovalent protein-ligand interactions and also investigate the kinetic of enzymatic reactions. The rate of glycolipids cleavage by the human neuraminidase 3 (hNEU3) was...
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Application of Machine Learning to Automate Classification and Information Extraction in Industrial Construction Documents
DownloadSpring 2022
Industrial construction projects are usually mega-projects that involve millions of labour person-hours and generate hundreds of thousands of documents. Construction documents represent a vital source of information and knowledge regarding the project scope. Documents come in different types and...