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- 4Chondrocytes
- 3Cryopreservation
- 3Vitrification
- 2Articular cartilage
- 2Cryoprotectant agents
- 4Chemical and Materials Engineering, Department of
- 4Chemical and Materials Engineering, Department of/Research Articles and Materials (Chemical and Materials Engineering)
- 4Surgery, Department of
- 4Surgery, Department of/Orthopaedic Surgery
- 4Graduate and Postdoctoral Studies (GPS), Faculty of
- 4Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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Spring 2023
Hyaline cartilage is a strong and flexible connective tissue found throughout the human body. It provides important structural and functional support for the nose, ribs, larynx, and trachea. Due to the avascular nature of the hyaline cartilage, its defects or lesions are non-regeneratable and...
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Arthritis in the Canadian Aboriginal population: north-south differences in prevalence and correlates
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Ng, Carmina, Chatwood, Susan, Young, T. Kue
"Background: Information on arthritis and other musculoskeletal disorders among Aboriginal people is sparse. Survey data show that arthritis and rheumatism are among the most commonly reported chronic conditions and their prevalence is higher than among non-Aboriginal people. Objective: To...
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2010
Law, G. K., Elliott, J. A., Forbes, J. F., Weiss, A. D., McGann, L. E., Jomha, N. M.
Large articular cartilage defects have proven difficult to treat and often result in osteoarthritis of the affected joint. Cryopreservation of articular cartilage can provide an increased supply of tissues for osteochondral allograft but cryoprotective agents are required; however, few studies...
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2012
Law, G. K., Forbes, J. F., Elliott, J. A., McGann, L. E., Jomha, N. M., Prasad, V., Almansoori, K. A.
Background Vitrification is a method of cryopreservation by which cells and tissues can be preserved at low temperatures using cryoprotective agents (CPAs) at high concentrations (typically ⩾6.0 M) to limit the harmful effects of ice crystals that can form during cooling processes. However, at...
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2014
Prasad, V., Laouar, L., Jomha, N. M., McGann, L. E., Fahmy, M. D., Almansoori, K. A., Elliott, J. A.
Vitrification of articular cartilage (AC) could enhance tissue availability but requires high concentrations of cyroprotective agents (CPAs). This study investigated relative injuries caused by commonly used CPAs. We hypothesized that the in situ chondrocyte dose–injury relationships of five...
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Spring 2014
Physical activity is recommended in the management of arthritis. This thesis utilized the CCHS 2007-2008 to 1) determine what factors modify physical activity in explaining the likelihood of having arthritis; and 2) what demographic, behavioural and medical factors influence physical activity...
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Fall 2019
Background: Up to 40% of patients are prescribed opioids prior to total knee arthroplasty (TKA) in the USA. These patients prescribed preoperative opioids have increased complications and worse outcomes after surgery. But, the impact of preoperative opioid use on patient-reported outcome (PRO)...
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Spring 2022
Juvenile idiopathic arthritis (JIA) is an inflammatory disease that can affect the temporomandibular joint (TMJ). TMJ-JIA can cause mandibular growth disturbances. Treatment options include medications targeting inflammation, orthodontic intervention, and surgeries; however, these medications are...
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2012
Elliott, J. A., Zhou, X., McGann, L. E., Adesida, A. B., Abazari, A., Law, G. K., Laouar, L., Forbes, J. F., Jomha, N. M., Maghdoori, B.
Articular cartilage injuries do not heal and large defects result in osteoarthritis with major personal and socioeconomic costs. Osteochondral transplantation is an effective treatment for large joint defects but its use is limited by the inability to store cartilage for long periods of time....