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Skip to Search Results- 2Bhaduri,Swayamdipta
- 1,Abdul Wasay
- 1Adam, Ibrahim S. Y.
- 1Azim, Mohammad Alaul
- 1Behboodi, Fahimeh
- 1Behnam Dehkordi, Mohammad
- 12Department of Electrical and Computer Engineering
- 11Department of Mechanical Engineering
- 5Department of Chemical and Materials Engineering
- 5Department of Chemistry
- 2Department of Physics
- 1Department of Agricultural, Food and Nutritional Science
- 2Backhouse, Christopher (Electrical and Computer Engineering)
- 2Doucette, John (Mechanical Engineering)
- 2Freeman, Mark (Physics)
- 2Mitra, Sushanta (Mechanical Engineering)
- 2Montemagno, Carlo (Chemical and Materials Engineering)
- 1Backhouse, Chris (Department of Electrical and Computer Engineering, University of Waterloo)
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A novel mouse model of acute antibody-mediated transplant rejection shows simultaneous complement activating and anti-inflammatory effects of donor specific IgG antibodies
DownloadFall 2013
We developed a small animal model of pure antibody-mediated rejection (ABMR) by utilizing fully major histocompatibility complex (MHC) mismatched kidney allografts in mice. By examining resultant ABMR pathology, we show that terminal complement products C5a and C5b-9 are crucial in establishing...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Spring 2017
One of the central puzzles concerning the interaction of low Reynolds number (Re<<1) fluid transport with bacterial biomass is the formation of filamentous structures called bacterial streamer. Bacterial streamers can be tethered at one or both ends to solid surfaces, while the rest of the...
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Fall 2010
Electro-transmittance of molecular junctions was characterized electrically and studied optically at 410nm and 532nm. Between 1kHz and 100kHz there was no qualitative difference between the control samples and the molecular junction samples, however there were difficulties with reproducibility of...
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Spring 2011
This dissertation investigates the size based separation of DNA molecules in nanoparticle arrays under asymmetric pulsed electrophoresis. Crystalline arrays of nanoparticles within microfluidic channels are fabricated using colloidal self-assembly, yielding structures with pore sizes ranging from...
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Design and Microfabrication of Robust and Highly Integrated Thermal Lab-On-A-Chip Polymeric Systems for Genetic Diagnosis
DownloadSpring 2014
The lab-on-chip (LOC) technology could transform and greatly enhance the health care system by making genetic diagnosis tests fast, accurate and readily accessible. However, most LOC systems are not prepared to resist variations of their external environment, as they depend upon many...
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Spring 2014
Lab-on-chip systems will be a major component in the future of health care. These technologies enable point-of-care testing by miniaturizing and improving the efficiency of many diagnostic techniques. Possible applications include the detection of various pathogens using genetic amplification...
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Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer
DownloadFall 2013
Conventional cytometry uses fluorescently labelled cells that are laborious and costly to prepare. Using a label-free technique, individual cells can be differentiated by light scattering patterns, a result of different physical attributes. This thesis describes the development of a microfluidic...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...