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2006
Wagner, James, Tegos, Theodore, Wan, Xiang, Lin, Guohui
Technical report TR06-10. Background: Accurately quantifying the signature information of chemical shifts provides a foundation for accurate and complete sequential resonance assignment in protein NMR spectroscopy. A nearly complete assignment is a prerequisite for three dimensional protein ...
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2003
Chen, Zhi-Zhong, Xu, Ying, Wen, Jianjun, Lin, Guohui, Jiang, Tao, Xu, Dong, Rizzi, Romeo
Technical report TR03-07. Protein NMR peak assignment refers to the process of assigning a group of \"spin systems\" obtained experimentally to a protein sequence of amino acids. The automation of this process is still an unsolved and challenging problem in NMR protein structure determination....
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2009
Goebel, Randy, Chen, Jiyang, Yu, Philip S., Zaiane, Osmar R.
Technical report TR09-02. The significant increase in open access digital information has created incredible opportunities for modern database research, especially in exploiting significant computational resources to determine complex relationships within those data. In this paper, we consider...
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2005
Xu, Dong, Wu, Xiaomeng, Wan, Xiu-Feng, Lin, Guohui, Gang, Wu
Technical report TR05-06. The availability of complete genomic sequences allows us to infer the evolutionary footprints between species in a global strategy. However, the length of these genomic sequences poses a challenge on computational efficiency and optimality of information representation...
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2015
Stothard, Paul, Wang, Yining, Lin, Guohui, Wylie, Tim
Background Despite ongoing reductions in the cost of sequencing technologies, whole genome SNP genotype imputation is often used as an alternative for obtaining abundant SNP genotypes for genome wide association studies. Several existing genotype imputation methods can be efficient for this...