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Skip to Search Results- 47Metabolomics
- 8Mass-spectrometry
- 6Chemical isotope labeling
- 5LC-MS
- 3Dansylation
- 3Metabolite identification
- 2Nam, Seo Lin
- 1Blackmore, Derrick
- 1Borzouie, Shima
- 1Bourrie, Benjamin C.T.
- 1Chan, Angela W
- 1Chen, Guanqun
- 45Graduate and Postdoctoral Studies (GPS), Faculty of
- 45Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Fall 2013
Cancer cachexia is a multifactorial syndrome characterized by involuntary weight loss, wasting of skeletal muscle driven by reduced food intake and abnormal metabolism. Cachexia has a negative impact on quality of life, response to chemotherapy and survival. Cachexia research is undeveloped with...
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Spring 2022
BackgroundEvidence is emerging that the gut microbiome is an important contributor to the weight and metabolic effects of bariatric surgery. However, the microbial and intestinal physiological changes that occur with bariatric surgery are poorly understood. Developing this understanding...
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Fall 2012
Pancreatic cancer is a leading cause of cancer-related death, due to its aggressive biology, lack of tools for early diagnosis and screening, advanced presentation and resistance to adjuvant therapy. Metabolomics, the newest of the “omics” sciences, may offer the potential for non-invasive...
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Fall 2015
Gastric cancer is an aggressive malignancy. Much of the mortality is attributable to delayed diagnosis from non-specific symptoms, and lack of early and accurate screening modalities. Metabolomics, the most downstream of the “omics” sciences (genomics, transcriptomics, proteomics) is the latest...
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Use of reconstituted kefir consortia to determine the impact of microbial composition on kefir metabolite profiles
Download2023-11-01
Bourrie, Benjamin C.T., Diether, Natalie, Dias, Ryan P., Nam, Seo Lin, de la Mata, A. Paulina, Forgie, Andrew J., Gaur, Gautam, Harynuk, James J., Gänzle, Michael, Cotter, Paul D., Willing, Benjamin P.
Kefir is fermented traditionally with kefir grains, but commercial kefir production often relies on fermentation with planktonic cultures. Kefir has been associated with many health benefits, however, the utilization of kefir grains to facilitate large industrial production of kefir is...
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Using 1H-NMR based metabolomics to investigate the pathological consequences of mitochondrial disease and human rabies infection
DownloadSpring 2012
Mitochondrial diseases encompass a wide range of clinical phenotypes. The etiology of these disorders is extremely complex; mitochondria are central to energy metabolism and dysfunction can have a profound effect on global metabolism. The original objective of this thesis was to use 1H-NMR based...
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Spring 2014
This thesis examines the pathophysiology of asthma, attempts to determine the cellular mechanisms behind viral-induced immune memory mediated asthma exacerbations, and investigates urinary metabolomic biomarkers of asthma and neonatal hypoxia.