Search
Skip to Search Results- 2Guan, Leluo
- 2Jin, Weiwu
- 1Abbasi Dezfouli, Meysam
- 1Ambrose, Divakar J.
- 1Beaudoin, Frédéric
- 1Beaulieu, Michael J.
- 11Graduate and Postdoctoral Studies (GPS), Faculty of
- 11Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 5Agricultural, Food and Nutritional Science, Department of
- 5Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Roy Berg Kinsella Research Ranch
- 1Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
- 3Department of Agricultural, Food, and Nutritional Science
- 1Department of Biomedical Engineering
- 1Department of Cell Biology
- 1Department of Physics
- 1Department of Physiology
- 1Department of Public Health Sciences
- 1Co-supervisor: Dr. Marc Mackenzie (Oncology)
- 1Damaraju, Sambasivarao (Medical Sciences - Laboratory Medicine and Pathology)
- 1Davidge, Sandra (Obstetrics/Gynecology and Physiology)
- 1Davis, Faith (School of Public Health)
- 1DeLorey, Darren Faculty of Kinesiology, Sport, and Recreation
- 1DeLorey, Darren S. (Physical Education and Recreation)
-
Construction of bovine whole-genome radiation hybrid and linkage maps using high-throughput genotyping
Download2007
Williams, J. L., Moore, S. S., Wang, Z., McKay, S. D., Murdoch, B. M.
High-density whole-genome maps are essential for ordering genes or markers and aid in the assembly of genome sequence. To increase the density of markers on the bovine radiation hybrid map, and hence contribute to the assembly of the bovine genome sequence, an Illumina® BeadStation was used to...
-
2008
Ambrose, Divakar J., Emmanuel, Daya G. V.
Abstract — An 8-month-old, virgin Holstein heifer with precocious mammary development was presented for examination. Protein, fat, and lactose in the mammary secretion were 14.90%, 0.12%, and 0.20%, respectively; somatic cell count was 3.9 3 10 6 /mL, with no bacterial infection. The heifer was...
-
Brain fatty acid-binding protein and ω-3/ω-6 fatty acids: Mechanistic insight into the poor prognosis of malignant glioma cell migration
Download2010
Godbout, Roseline, Mita, Raja, Field, Catherine J., Beaulieu, Michael J.
Malignant gliomas (MG) are highly infiltrative tumors that consistently recur despite aggressive treatment. Brain fatty acid-binding protein (FABP7), which binds docosahexaenoic acid (DHA) and arachidonic acid (AA), localizes to sites of tumor infiltration and is associated with a poor prognosis...
-
Analytical considerations and biology of milk conjugated linoleic acid synthesis in the bovine
DownloadSpring 2010
Biosynthesis of milk conjugated linoleic acid (CLA), a component of milk fat with demonstrated health benefits, requires a dietary source of PUFA. Even with PUFA supplementation, milk CLA is highly variable. Therefore, this study was aimed at identifying factors responsible for the variations in...
-
Lipid Modified Polymers for Transfection of Human CRL Fibroblasts, and for siRNA Mediated MDR Reversal in Melanoma Cancer Therapy
DownloadFall 2010
Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...
-
Hsp90 and its co-chaperones regulate the activity of human Argonaute2 in RNA-mediated silencing pathways
DownloadFall 2011
The potent ability of small, double-stranded RNAs to silence gene expression was initially reported 1998, sparking revolutions in molecular biology and genetics. Since then, intensive research into the mechanism of RNA-mediated silencing has implicated the machinery of this pathway in the...
-
Spring 2012
Ovarian endocrine function has a major impact on homeostatic mechanisms in the cardiovascular system in women. In particular, estrogens play an important role in the regulation of vascular function. Epidemiological and experimental evidence links increased risk for cardiovascular disease with...
-
Development of a porcine (Sus scofus) embryo-specific microarray: Annotation and validation
Download2012
Dobrinsky, John, Zhou, Chi, Pasternak, J. Alexander, Dyck, Michael K., Foxcroft, George R., Nieminen, Julie, Tsoi, Stephen, Rigault, Philippe, Sirard, Marc-André, Robert, Claude, Grant, Jason R.
Background The domestic pig is an important livestock species and there is strong interest in the factors that affect the development of viable embryos and offspring in this species. A limited understanding of the molecular mechanisms involved in early embryonic development has inhibited our...
-
Drug Resistance in Breast Cancer: Characterization of Rationally Designed Paclitaxel Analogs in Model Systems
DownloadFall 2013
Breast cancer is a leading cause of cancer related deaths among women in the developed world. Treatment options for breast cancer include taxanes, which mediate cytotoxic effects by inducing microtubule polymerization which impedes cell division. Taxane resistant breast cancer is a mounting...
-
Fall 2013
Intrafractional tumour tracking is of considerable interest as a means to minimize the PTV in treating mobile tumours. By utilizing the intrafractional MR imaging feature of linac-MR, this thesis seeks to develop a direct, non-surrogate based intrafractional tumour tracking system, and physically...