This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
Search
Skip to Search Results- 11Bioinformatics
- 2Machine Learning
- 2Metabolomics
- 13 Tier Architecture
- 1AntiC
- 1Artificial Intelligence
- 1Bandi Kenari, Nahid
- 1Carroll, Kristin
- 1Damavandi, Babak
- 1Jewison, Timothy
- 1Jing, Anqi
- 1Khan, Sheehan Veikko
-
Spring 2014
Metabolomics involves the high throughput characterization of small molecules or metabolites in cells, tissues and organisms. To interpret, store and exchange metabolomic data it is necessary to have comprehensive, electronically accessible databases that can be used to handle both the...
-
Fall 2011
Metabolomics aims to study all small-molecule compounds (i.e. metabolites) in cells, tissues, or biofluids. These compounds provide a functional readout of the physiological, developmental, and pathological state of a biological system. The field of metabolomics has expanded rapidly over the last...
-
eHealth and mHealth Pipelines for Clinical Decision Support to Improve Medication Selection and Safety
DownloadFall 2015
Although much work has been done over the past decade on developing personalized and evidence-based medicine, such as diagnostic tests based on genetics to better predict patients' responses to therapy, stumbling blocks remain that have prevented knowledge, tests, and other pertinent...
-
Spring 2012
Recent advances in high-throughput technologies, such as genome-wide SNP analysis and microar- ray gene expression profiling, have led to a multitude of ranked lists, where the features (SNPs, genes) are sorted based on their individual correlation with a phenotype. Multiple reviews have shown...
-
Fall 2023
Drinking water treatment is a necessary practice for the elimination of waterborne disease. The study of drinking water treatment can be challenging as large portions of the composition of the source water used by treatment plants remains unknown. In Chapter 1, I review the importance of drinking...
-
Inference of epigenetic subnetworks and expression-based analysis using a breast cancer dataset
DownloadFall 2018
Changes in gene expression have been thought to play a crucial role in various types of cancer. With the advance of high-throughput experimental techniques, many genome-wide studies are underway to analyze underlying mechanisms that may drive the changes in gene expression. It has been observed...
-
Investigation of Causal Mutations in Livestock and Companion Animals Using Whole-Genome Sequencing (WGS) and Bioinformatics
DownloadSpring 2024
In this thesis project, three studies were conducted, aimed at identifying the causal variants responsible for phenotypic/genotypic sex discordance in cattle, copper toxicosis in Dalmatian dogs, and low fertility/infertility in cattle. In all three studies, whole-genome sequencing (WGS) and...
-
Fall 2024
The COVID-19 pandemic accelerated the development of mRNA vaccines, yet iden- tifying the optimal mRNA sequence for human use, particularly for the SARS-CoV- 2 spike protein, remains challenging. This thesis focuses on optimizing the open reading frame (ORF), a crucial mRNA component composed of...
-
Fall 2016
The field of biomedicine is reeling from “information overload”. Indeed, biomedical researchers find it almost impossible to stay current with published literature due to the vast amounts of data being generated and published. As a result, they are turning to text mining. Over the past two...