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Skip to Search Results- 5Articular cartilage
- 5Vitrification
- 3Cryopreservation
- 3Cryoprotectant agents
- 3Statistical analysis
- 2Chondrocytes
- 6Chemical and Materials Engineering, Department of
- 6Chemical and Materials Engineering, Department of/Research Articles and Materials (Chemical and Materials Engineering)
- 6Surgery, Department of
- 6Surgery, Department of/Orthopaedic Surgery
- 1Geotechnical and Geoenvironmental Engineering Program
- 1Geotechnical and Geoenvironmental Engineering Program/Journal Articles (Geotechnical & Geoenvironmental Engineering)
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2013
Yu, H., Jomha, N. M., Elliott, J. A., Al-Abbasi, K. K., McGann, L. E.
In previous research, we successfully cryopreserved intact human articular cartilage on its bone base with high chondrocyte viability using a vitrification protocol that entailed sequential exposure to several cryopreserving agents (CPAs) at lowering temperatures resulting in a high final...
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2010
Law, G. K., Elliott, J. A., Forbes, J. F., Weiss, A. D., McGann, L. E., Jomha, N. M.
Large articular cartilage defects have proven difficult to treat and often result in osteoarthritis of the affected joint. Cryopreservation of articular cartilage can provide an increased supply of tissues for osteochondral allograft but cryoprotective agents are required; however, few studies...
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2012
Law, G. K., Forbes, J. F., Elliott, J. A., McGann, L. E., Jomha, N. M., Prasad, V., Almansoori, K. A.
Background Vitrification is a method of cryopreservation by which cells and tissues can be preserved at low temperatures using cryoprotective agents (CPAs) at high concentrations (typically ⩾6.0 M) to limit the harmful effects of ice crystals that can form during cooling processes. However, at...
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2014-09-26
Rekieh, K., Abazari, A., Elliott, J.A., Jomha, N.M., Law, G.K., McGann, L.E.
Objective: Osteochondral allografting is an effective method to treat large osteochondral defects but difficulties in tissue preservation have significantly limited the application of this technique. Successful cryopreservation of articular cartilage (AC) could improve the clinical availability...
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2005
Cruden, D. M., Morgenstern, N. R., El-Ramly, H.
A probabilistic slope analysis methodology based on Monte Carlo simulation using Microsoft Excel and @Risk software is applied to investigate the failure of the Shek Kip Mei cut in Hong Kong. The study demonstrates the techniques used in quantifying uncertainties in shear strength of granitic...
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Statistical prediction of the vitrifiability and glass stability of multi-component cryoprotective agent solutions.
Download2010
Forbes, J. F., Law, G. K., Weiss, A. D., Scheuerman, A., McGann, L. E., Elliott, J. A., Jomha, N. M.
Long-term biologic storage of articular cartilage has proven elusive due to cellular degradation over time or acute damage during attempts at cryopreservation. Vitrification is one option that may result in successful cryopreservation but difficulty with cryoprotective agent (CPA) toxicity at...
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2013
Arppe, Antti, Newman, John, Han, Weifang
Shanghainese is an extremely topic-prominent language with many topic markers in competition with one another, often without any obvious basis for the selection of one topic marker over another. We explore the influence of five variables on the five most frequent topic markers in a corpus of...
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2012
Elliott, J. A., Zhou, X., McGann, L. E., Adesida, A. B., Abazari, A., Law, G. K., Laouar, L., Forbes, J. F., Jomha, N. M., Maghdoori, B.
Articular cartilage injuries do not heal and large defects result in osteoarthritis with major personal and socioeconomic costs. Osteochondral transplantation is an effective treatment for large joint defects but its use is limited by the inability to store cartilage for long periods of time....