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Skip to Search Results- 1Aguirre Monroy, Angelica M
- 1Alam, Kazi, MM
- 1Avis, Jillian LS
- 1Baleja, James D.
- 1Booker, Brandon K.
- 1Chehel Amirani, Morteza
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A Coarse-Grained Simulation Framework to Study Polyethylenimine-DNA Nanoparticles in Gene Delivery
DownloadSpring 2022
Cellular DNAs contain genetic information vital for the functioning of the cells. Corruption of this information, or genetic disorders, can lead to various diseases. A potential treatment is to deliver exogenous DNAs with the correct genetic information to malignant cells to achieve a...
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Assessing the Feasibility of Learning Biomedical Phenotype Patterns Using High-Throughput Omics Profiles
DownloadSpring 2014
A decade after the completion of the human genome project, the rapid advancement of the high-throughput measurement technologies has made omics (genomics, epigenomics, transcriptomics, metabolomics) profiling feasible. The availability of such omics profiles has raised the hope for the...
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Spring 2014
Benzo[a]pyrene diol epoxide (BPDE), a known carcinogen, is a reactive metabolite of benzo[a]pyrene (BP). BP is usually formed during combustion of organic substances, such as cigarette smoke, automobile emission exhaust, and industrial waste burning. BPDE can covalently bind to the nucleobases of...
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Developing and Assessing an Environmental DNA Protocol for Detecting Amphibian Species in Lentic Systems in Alberta, Canada
DownloadSpring 2016
Global declines of amphibian populations have resulted in increased interest in determining and monitoring the geographic ranges for both endangered and invasive amphibian species. Monitoring programs rely on detection techniques to amass data, techniques that must be dependable in order to...
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Fall 2014
The first part of this study is a narrative literature review to provide an overview of the methods used to assess dietary diversity. The second part of this study is a case study to explore the factors affecting dietary diversity as well as the perceptions of a kitchen garden intervention in...
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DNA-assisted Heterogeneous Integration of Micro- and Nanoelectronic Devices: Modeling, Control, and Rational Design of Selective Attachment
DownloadSpring 2018
Heterogeneous integration is an electronic packaging approach that enables the fabrication and assembly of complete electronic subsystems from components fabricated with different substrates and processes. Current commercial techniques like robotic pick-and-place, fluidic self-assembly, and...
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Factors affecting the detectability and eastern distribution of grizzly bears in Alberta, Canada
DownloadFall 2013
Effective and adaptive conservation of a species requires knowledge of trend in abundance and distribution. Monitoring species that are highly mobile, cryptic, and occurring at low densities is especially challenging. This research investigates the local factors affecting the detectability of...
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Impact of Farming Practices on Soil Bacterial Community Composition, Diversity, and Interactions in the Main Agricultural Regions of Alberta
DownloadSpring 2022
Soil health refers to “the capacity of soil to function as a vital living system”, implying not only the capacity of soil to providing services of human interest, but also its capacity to provide ecological services, which makes ecosystems sustainable for the long term. The assessment of soil...
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Molecular Dynamics Simulations of Polyethylenimine Mediated Nucleic Acid Complexation with Implications for Non-viral Gene Delivery
DownloadSpring 2013
Gene therapy is a promising therapeutic technique that involves delivering nucleic acids into cells. Polycations have evolved into a major category of gene carriers. Polyethylenimine (PEI) is one of the most effective polycationic carriers. Furthermore, modifying PEI with certain lipophilic...