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Skip to Search Results- 20Plastow, Graham S.
- 17Harding, John C. S.
- 11Stothard, Paul
- 9Lunney, Joan K.
- 8Bao, Hua
- 8Dekkers, Jack C. M.
- 20PigGen Canada
- 20PigGen Canada/Journal Articles
- 7Roy Berg Kinsella Research Ranch
- 7Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
- 6Agricultural, Food and Nutritional Science, Department of
- 6Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection
Download2020-01-01
Van Goor, Angelica, Pasternak, Alex, Walker, Kristen, Hong, Linjun, Malgarin, Carolina, MacPhee, Daniel J., Harding, John C. S., Lunney, Joan K.
Background:A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However,the mechanisms leading to variation in fetal outcome in response to PRRSV...
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Putting the microbiota to work: Epigenetic effects of early life antibiotic treatment are associated with immune-related pathways and reduced epithelial necrosis following Salmonella Typhimurium challenge in vitro
Download2020-04-01
Costa, Matheus O., Fouhse, Janelle, Silva, Ana Paula P., Wiling, Benjamin, Harding, John C. S.
Salmonella enterica serovar Typhimurium is an animal welfare and public health concern due to its ability to parasite livestock and potentially contaminate pork products. To reduce Salmonella shedding and the risk of pork contamination, antibiotic therapy is used and can contribute to...
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Type 2 porcine reproductive and respiratory syndrome virus infection increases apoptosis at the maternal-fetal interface in late gestation pregnant gilts
Download2017-03-01
Novakovic, Predrag, Harding, John C. S., Al-Dissi, Ahmad N., Detmer, Susan E.
The pathogenesis of fetal death associated with porcine reproductive and respiratory syndrome (PRRS) is hypothesized to be a consequence of PRRS virus-induced apoptosis at the maternal-fetal interface (MFI). The objectives of this study were to evaluate distribution and degree of apoptosis in the...
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Relationships of CD163 and CD169 positive cell numbers in the endometrium and fetal placenta with type 2 PRRSV RNA concentration in fetal thymus
Download2016-08-05
Novakovic, Predrag, Harding, John C. S., Ladning, Andrea, Al-Dissi, Ahmad N., MacPhee, Daniel J., Detmer, Susan E.
Several routes of porcine reproductive and respiratory virus PRRSV transmission across the porcine diffuse epitheliochorial placentation have been proposed, but none have been proven. The objectives of this study were to investigate associations between numbers of CD163 and CD169 positive...
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2003
Day, Andy E., Andersson, Leif, Plastow, Graham S., Pielberg, Gerli
Gene duplications are common in the vertebrate genome, and duplicated loci often show a variation in copy number that may have important phenotypic effects. Here we describe a powerful method for quantification of duplicated copies based on pyrosequencing. A reliable quantification was obtained...
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A first generation whole genome RH map of the river buffalo with comparison to domestic cattle
Download2008
Santana, Andre M., Tonhati, Humberto, Greco, Anthony J., Mishra, Bina, Cai, Zhipeng, Kumar, S. T. Bharani, Tantia, Madhu S., Jones, Brittany C., Saradhi, G. Pardha, Miziara, Melissa N., Kumar, M. Aravind, Kochan, Kelli J., Goldammer, Tom, Brunner, Ronald M., Caetano, Alexandre R., Weikard, Rosemarie, Womack, James E., Mathew, Boby, Kumar, Satish, Pelai, Vanderlei A., Filho, Edson A. R., Jeong, Jooha, Prasad, Aparna, Vijh, Ramesh K., Lin, Guohui, Moore, Stephen, Galvao, Stephan R., Mariani, Paola, Grant, Jason R., Stafuzza, Nedenia B., Fornitano, Larissa C., Riggs, Penny K., Stothard, Paul, Amaral, M. Elisabete
Background The recently constructed river buffalo whole-genome radiation hybrid panel (BBURH5000) has already been used to generate preliminary radiation hybrid (RH) maps for several chromosomes, and buffalo-bovine comparative chromosome maps have been constructed. Here, we present the...
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A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project
Download2015-10-26
Arantes, Adriano S., Coros, Colin, Moore, Stephen, Liao, Xiaoping, Crowley, John J., Sargolzaei, Mehdi, Miller, Stephen P., Schenkel, Flavio, Stothard, Paul, Basarab, John A., De Pauw, Mary, Plastow, Graham S.
Background The Canadian Cattle Genome Project is a large-scale international project that aims to develop genomics-based tools to enhance the efficiency and sustainability of beef and dairy production. Obtaining DNA sequence information is an important part of achieving this goal as it...
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Bioinformatic analyses in early host response to Porcine Reproductive and Respiratory Syndrome virus PRRSV reveals pathway differences between pigs with alternate genotypes for a major host response QTL
Download2016-03-08
Bao, Hua, Schroyen, Martine, Rowland, Robert R.R., Guan, Le L., Stothard, Paul, Reecy, James M., Fritz-Waters, Eric, Koltes, James E., Kommadath, Arun, Plastow, Graham S., Eisley, Christopher, Tuggle, Christopher K. , Dekkers, Jack C.M., Lunney, Joan K., Choi, Igseo
Background A region on Sus scrofa chromosome 4 (SSC4) surrounding single nucleotide polymorphism (SNP) marker WUR10000125 (WUR) has been reported to be strongly associated with both weight gain and serum viremia in pigs after infection with PRRS virus (PRRSV). A proposed causal mutation in the...
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2012
Stothard, Paul, Arantes, Adriano S., Grant, Jason R.
Background Continued sequencing efforts coupled with advances in sequencing technology will lead to the completion of a vast number of small genomes. Whole-genome comparisons represent an important part of the analysis of any new genome sequence, as they can provide a better understanding of the...
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Comparison of host genetic factors influencing pig response to infection with two North American isolates of porcine reproductive and respiratory syndrome virus
Download2016-01-01
Hess, Andrew S., Islam, Zeenath, Hess, Melanie K., Rowland, Raymond R. R., Lunney, Joan K., Doeschl-Wilson, Andrea, Plastow, Graham S., Dekkers, Jack C. M.
Background:Porcine reproductive and respiratory syndrome (PRRS) is one of the most important swine diseases in the world and genetic selection of pigs for increased resistance to PRRS is an attractive method to improve the health status of the swine herd. This study compared phenotypic and...