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Putting the microbiota to work: Epigenetic effects of early life antibiotic treatment are associated with immune-related pathways and reduced epithelial necrosis following Salmonella Typhimurium challenge in vitro
Download2020-04-01
Costa, Matheus O., Fouhse, Janelle, Silva, Ana Paula P., Wiling, Benjamin, Harding, John C. S.
Salmonella enterica serovar Typhimurium is an animal welfare and public health concern due to its ability to parasite livestock and potentially contaminate pork products. To reduce Salmonella shedding and the risk of pork contamination, antibiotic therapy is used and can contribute to...
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RESEARCHOpen AccessDevelopment of a 3D printed device tosupport long term intestinal culture as analternative to hyperoxic chamber methods
Download2017-01-01
Costa, Matheus O., Nosach, Roman, Harding, John C. S.
Background:Most interactions between pathogenic microorganisms and their target host occur on mucosal surfaces of internal organs such as the intestine. In vitro organ culture (IVOC) provides an unique tool for studyinghost-pathogen interactions in a controlled environment. However, this...