Journal Articles (Chemistry)

2009

Kitova, Elena N., Klassen, John S., Sun, Nian, Sun, Jiangxiao

The application of the reporter molecule (Mrep) method for identifying nonspecific complexes in the ES-MS analysis of protein-ligand and DNA-ligand interactions in vitro is described. To test the reliability of the method, it was applied to the ES-MS analysis of protein-carbohydrate complexes...

2018-01-01

Shu, Tong, Shen, Qiming, Su, Lei, Zhang, Xi, Serpe, Michael J.

Poly(N-isopropylacrylamide)-co-(acrylic acid) (pNIPAm-co-AAc) microgels incorporated with CuS nanoparticles (CuSNPs) were synthesized and employed for near-infrared (NIR) triggered photothermal killing of cancer cells. Cu2+ was enriched in the microgels through deprotonation of the pNIPAm-co-AAc...

2016

Bramucci, Anna R., Labeeuw, Leen, Khey, Joleen, Case, Rebecca J., de la Mata, A. Paulina, Harynuk, James, Atwal, Harjot

Indole-3-acetic acid (IAA) is an auxin produced by terrestrial plants which influences development through a variety of cellular mechanisms, such as altering cell orientation, organ development, fertility, and cell elongation. IAA is also produced by bacterial pathogens and symbionts of plants...

2016

Klassen, John S., Yao, Yuyu, Kitova, Elena N., Richards, Michele R.

The results of an investigation into the influence of sulfolane, a commonly used supercharging agent, on electrospray ionization mass spectrometry (ESI-MS) measurements of protein–ligand affinities are described. Binding measurements carried out on four protein–carbohydrate complexes, lysozyme...

2016

Klassen, John S., Yao, Yuyu, Kitova, Elena N., Richards, Michele R.

The results of an investigation into the influence of sulfolane, a commonly used supercharging agent, on electrospray ionization mass spectrometry (ESI-MS) measurements of protein–ligand affinities are described. Binding measurements carried out on four protein–carbohydrate complexes, lysozyme...

2018-01-01

Dempster, Steve P., Sasidharanpillai, Swaroop, Loppnow, Glen R.

The effect of the N1 ribose sugar on the initial excited‐state structural dynamics of uridine is explored with ultraviolet resonance Raman spectroscopy. Excited‐state slopes and broadening parameters were obtained by simulating the resonance Raman excitation profiles and absorption spectrum using...

2019-01-01

Bernard, G.M., Michaelis, V.K.

High‐field dynamic nuclear polarization nuclear magnetic resonance (DNP NMR) spectroscopy is rapidly emerging as a revolutionary analytical structural method by greatly enhancing the sensitivity of nuclear magnetic resonance. Innovative solutions are constantly being introduced to address the...

2020-04-20

Howlader, Md. Amran, Guo, Tianlin, Chakraberty, Radhika, Cairo, Christopher W.

The human neuraminidase enzymes (NEU1, NEU2, NEU3, and NEU4) are a class of enzymes implicated in pathologies including cancer and diabetes. Several reports have linked neuraminidase activity to the regulation of cell migration in cancer cells. Using an in vitro cell migration assay on...

2018-01-01

Islam, Molla R., Azimi, Shakiba, Teimoory, Faranak, Loppnow, Glen R., Serpe, Michael J.

In this investigation, we show that RNA can be separated from a solution containing DNA and RNA and the isolated RNA can be detected using poly (N-isopropylacrylamide-co-N-(3-aminopropyl) methacrylamide hydrochloride) microgel-based optical devices (etalons). The isolation of RNA was accomplished...

2017-01-01

Xu, Wenwen, Wei, Menglian, Serpe, Michael J.

A facile self‐assembly method is presented to prepare poly(N‐isopropylacrylamide)‐based microgels modified anisotropically with gold nanoparticles (Au NPs) to yield Janus microgels. Transmission electron microscopy is used to confirm that microgels are selectively coated on one or both sides with...