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Spring 2016
The increased use of digital devices in the home for work, communication, entertainment, and information searching makes these devices attractive to young children, who learn to communicate by observing and interacting with family members. This qualitative study examined 11 Canadian and...
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A comprehensive assessment of peroxisome biology: ER-dependent peroxisome proliferation control, evolution of organelle inheritance in yeast and a Drosophila model system of Zellweger syndrome
DownloadFall 2013
The modern eukaryotic cell is a meshwork of encapsulating membranes that compartmentalize many distinct biochemical processes. It is complex. This complexity facilitates the many unique and diverse processes that aid the eukaryote in its growth, division and adaptation to its environment. A...
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Fall 2017
The voltage-gated KCNQ1/KCNE1 potassium ion channel plays a key role in maintaining the heart rhythm. An active channel generates the slow delayed rectifier (IKs) current in the heart. Both loss-of-function and gain-of-function mutations in KCNQ1 or KCNE1 are linked to many heart-related...
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A Comprehensive Dynamical Model for Human CaV1.2 Ion Channel: Structural and Functional Studies
DownloadFall 2019
Human CaV1.2 is a voltage-gated calcium channel (VGCC), which plays an essential role to maintain a normal cardiac function. Any abnormalities in CaV1.2 can lead to serious cardiac diseases (e.g. cardiac arrhythmias and Timothy syndrome). Thus, understanding the structure-function-dynamics...
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A comprehensive examination of outdoor play in licensed childcare centres in Alberta, Canada
DownloadFall 2019
Background Children engage in more active play when they are outside compared to inside. With a large proportion of children attending childcare outside of the home, childcare centres have been identified as important setting for children’s outdoor play. However, the duration and frequency of...