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2015

Xiao, Changchun., Gonzalez-Martin, Alicia, Miletic, Ana V., Rickert, Robert C., Head, Steven R., Knight, Sarah, , Macauley, Matthew S., Lai, Maoyi, Jin, Hyun Y., Sabouri-Ghomi, Mohsen

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly to endogenous miRNAs. Here we show that transient transfection of...

2015

Zhong, Weiming, Quigley, Christina, Klassen, John S., Fang, Hao, Jiang, Xi, Wei, Chao, Tan, Ming, Xia, Ming, Huang, Pengwei, Fan, Qiang, Zhang, Xufu

The recent discovery that human noroviruses (huNoVs) recognize sialic acids (SAs) in addition to histo-blood group antigens (HBGAs) pointed to a new direction in studying virus-host interactions during calicivirus infection. HuNoVs remain difficult to study due to the lack of an effective cell...

2017-01-01

Zhou, B., Faucher, A., Laskowski, R., Terskikh, V.V., Kroeker, S., Sun, W., Lin, J., Mi, J-X., Michaelis, V.K., Pan, Y.

A series of well-characterized magnesium borate minerals and synthetic analogues have been studied via ultrahigh-field 25Mg solid-state NMR spectroscopy. Correlations between 25Mg NMR parameters and the local structure at the magnesium site(s) are highlighted and discussed. First-principles...

2018-01-01

Michaelis, V.K., Levin, K., Germanov, Y., Lelong, G., Kroeker, S.

The functional importance of lithium in many types of materials requires reliable methods for studying its local structure and dynamics. Nuclear magnetic resonance (NMR) spectroscopy should be ideal for this purpose but suffers from poor resolution due to intrinsic dipolar broadening. We overcome...

2016-01-01

Li, Xue, Serpe, Michael J.

By depositing layers composed of poly (N‐isopropylacrylamide)‐based microgels and the polyelectrolyte polydiallyldimethylammonium chloride on a flexible substrate, responsive materials that bend upon drying can be fabricated; the extent of the bending depends on atmospheric humidity. This study...

2014

Harynuk, James, Adutwum, Lawrence A.

Using raw GC/MS data as the X-block for chemometric modeling has the potential to provide better classification models for complex samples when compared to using the total ion current (TIC), extracted ion chromatograms/profiles (EIC/EIP), or integrated peak tables. However, the abundance of raw...

2015

McBride, Ryan, Wang, Shui-Hua , Macauley, Matthew S., Khoo, Kay-Hooi, Paulson, James C., Kannagi, Reiji, Peng, Wenjie, He, Yuan, Kawasaki, Norihito, Arlian, Britni M.

CD22 is an inhibitory B-cell co-receptor whose function is modulated by sialic acid (Sia)-bearing glycan ligands. Glycan remodeling in the germinal center (GC) alters CD22 ligands, with as yet no ascribed biological consequence. Here, we show in both mice and humans that loss of high affinity...

2017-04-18

Mariusz Klobukowski

These basis sets were prepared using the new well-tempered formula introduced by S. Huzinaga and B. Miguel (Chem. Phys. Lett., 175 (1990) 289-291): ζ(N) = α ζ(N−k+1) = ζ(N−k+2) * β * [ 1+ γ (k/N)^δ ] , k = 2, ... ,N where α, β, γ, and δ are parameters (common for the radial functions of all...