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Skip to Search Results- 69Klassen, John S.
- 54Serpe, Michael J.
- 52Kitova, Elena N.
- 18Michaelis, V.K.
- 17Gao, Yongfeng
- 14Loppnow, Glen R.
- 20Electrospray ionization mass spectrometry
- 14Etalons
- 13SSNMR
- 12Affinity
- 12Stimuli-Responsive Polymers
- 11Complexes
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Formation of meta-Substituted Phenols by Transition Metal-Free Aromatization: Use of 2-Bromocyclohex-2-en-1-ones.
Download2016-01-01
Yu, Guojun, Clive, Derrick L. J.
Addition of Grignard- or other organometallic reagents to 3-halocyclohex-2-en- 1-ones bearing an alkyl or aryl group at C-5, followed by mild acid treatment and exposure to DBU at room temperature, generates meta-substituted phenols in which the newly introduced meta substituent originates from...
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2014
Serpe, Michael J., Xu, Wenwen, Gao, Yongfeng
Poly (N-isopropylacrylamide-co-acrylic acid) (pNIPAm-co-AAc) microgel-based free-standing etalons have been developed by fabricating etalons on a solid support that has been coated with a sacrificial polymer layer. Therefore, the etalon could be easily removed from the solid substrate upon...
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2017-05-04
Dynamic nuclear polarization (DNP) NMR spectroscopy, a high-polarization method, is rapidly changing the landscape of what is possible in solid-state nuclear magnetic resonance spectroscopy. To date, there have been over 200 publications discussing high-frequency DNP NMR of solids with more than...
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High-Frequency Dynamic Nuclear Polarization NMR for Solids: Part 2 – Development and Applications
Download2017-01-01
High-frequency dynamic nuclear polarization nuclear magnetic resonance (DNP NMR) spectroscopy is having a major impact on the far-reaching abilities of solid-state NMR. This high-sensitivity technique made possible by transferring high polarization from an unpaired electron source to an...
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Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies
Download2016
Hsueh, Jessica, Menis, Sergey, Sanders, Rogier W., Ozorowski, Gabriel, Pauthner, Matthias, Voss, James E., van Gils, Marit J., Torres, Jonathan L., McCoy, Laura E., Ward, Andrew B., Wilson, Ian A., Schief, William R., Macauley, Matthew S., Burton, Dennis R., Cottrell, Christoph A., Messmer, Terrence, Sok, Devin, Briney, Bryan, Kulp, Daniel W.
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope trimer (BG505 SOSIP.664) that can induce robust autologous Tier 2 neutralization. Here, potently neutralizing monoclonal antibodies (nAbs) from rabbits immunized with BG505 SOSIP.664 are shown to...
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Human neuraminidase isoenzymes show variable activities for 9-O-acetyl-sialoside substrates
Download2018-01-16
Hunter, Carmanah D, Khanna, Neha, Richards, Michele R, Darestani, Reza Rezaei, Zou, Chunxia, Klassen, John S, Cairo, Christopher W.
Recognition of terminal sialic acids is central to many cellular processes, and structural modification of sialic acid can disrupt these interactions. A prominent, naturally occuring, modification of sialic acid is 9-O-acetylation (9-O-Ac). Study of this modification through generation and...
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Identifying carbohydrate ligands of a norovirus P particle using a catch and release electrospray ionization mass spectrometry assay
Download2014
Jiang, Xi, Kitova, Elena N., Klassen, John S., Tan, Ming, Han, Ling
Noroviruses (NoVs), the major cause of epidemic acute gastroenteritis, recognize human histo-blood group antigens (HBGAs), which are present as free oligosaccharides in bodily fluid or glycolipids and glycoproteins on the surfaces of cells. The subviral P particle formed by the protruding (P)...
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Identifying carbohydrate ligands of a norovirus P particle using a catch and release electrospray ionization mass spectrometry assay
Download2014
Jiang, Xi, Kitova, Elena N., Klassen, John S., Tan, Ming, Han, Ling
Noroviruses (NoVs), the major cause of epidemic acute gastroenteritis, recognize human histo-blood group antigens (HBGAs), which are present as free oligosaccharides in bodily fluid or glycolipids and glycoproteins on the surfaces of cells. The subviral P particle formed by the protruding (P)...
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Identifying nonspecific ligand binding in electrospray ionization mass spectrometry using the reporter molecule method
Download2009
Kitova, Elena N., Sun, Jiangxiao, Sun, Nian, Klassen, John S.
The application of the reporter molecule (Mrep) method for identifying nonspecific complexes in the ES-MS analysis of protein-ligand and DNA-ligand interactions in vitro is described. To test the reliability of the method, it was applied to the ES-MS analysis of protein-carbohydrate complexes...
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Identifying nonspecific ligand binding in electrospray ionization mass spectrometry using the reporter molecule method
Download2009
Sun, Nian, Klassen, John S., Kitova, Elena N., Sun, Jiangxiao
The application of the reporter molecule (Mrep) method for identifying nonspecific complexes in the ES-MS analysis of protein-ligand and DNA-ligand interactions in vitro is described. To test the reliability of the method, it was applied to the ES-MS analysis of protein-carbohydrate complexes...