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- 1Arctic Canada
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Can Existing Cohort Studies with Self-Reported Diagnosis be used in the Study of Rare Cancer? Evaluating the Feasibility of Rare Cancer Research in Emerging Cohorts in Canada
DownloadFall 2019
Rare cancers affect few people individually, but collectively account for approximately 22% of new cancer cases in Canada. However, prevention and population-level research on rare cancers have been limited as low case numbers make them difficult to study. The emergence of large, collaborative...
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Physical Activity in Hypermobile Ehlers-Danlos Syndrome and Generalized Hypermobility Spectrum Disorder
DownloadSpring 2024
Hypermobile Ehlers-Danlos Syndrome and Generalized Hypermobility Spectrum Disorder (hEDS/G-HSD) are two connective tissue disorders that are tightly intertwined as they both result in joint hypermobility-induced musculoskeletal manifestations and are placed on the same clinical spectrum. The...
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Spring 2019
Childhood cancer survivorship has increased drastically over the previous several decades, consequently increasing the frequency of chronic conditions in survivors. Female childhood cancer survivors are at an increased risk of developing nonsurgical premature menopause (NSPM) due to toxicities...
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Spring 2021
The number of childhood cancer survivors has dramatically increased in the past few decades due to advances in cancer treatment, shifting the priority from clinical treatment to improving long-term survivors’ quality of life. One late effect that greatly impacts female survivors is premature...
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Risk Prediction of Primary Ovarian Insufficiency in Childhood Cancer Survivors Using Polygenic Risk Scores and Clinical Risk Score
DownloadSpring 2022
Thanks to the advancement in cancer treatments, most children diagnosed with cancer are long-term survivors. However, it is estimated that two-thirds of childhood cancer survivors will develop chronic diseases later in life due to their cancer treatments. A reproductive late effect in female...
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Fall 2020
Helicobacter pylori (Hp) infection has an elevated prevalence in northern Indigenous communities in Canada. This thesis investigates social inequities in the Hp-associated disease burden within Indigenous communities in the Northwest Territories and Yukon. I examined how deprivation indicators...