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Skip to Search Results- 1Al Sayah, Fatima
- 1Alibhai, Arif A
- 1Aung, Yin N
- 1Belletrutti, Mark J
- 1Benjaminy, Shelly
- 1Colmers, Isabelle N.
- 4Systematic reviews
- 3Pediatrics
- 2Adjuvant chemotherapy
- 2Cardiovascular diseases
- 2Outcomes
- 1Adolescent depression
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Spring 2013
Occupational exposures in swine operations are associated with increased risk of respiratory problems. Although the etiology is not fully understood, genetic and environmental factors play important roles. The primary objective of this thesis is to explore effects of polymorphisms in the...
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Fall 2011
This thesis aimed to investigate congestive heart failure (CHF) associated with anthracycline exposures among the childhood cancer survivors, trying to identify differential anthracycline effects by genotype of certain genes. We had 130 childhood cancer survivors who developed CHF as cases and...
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Fall 2013
There is a general agreement that a relationship exists between health literacy (HL) and health outcomes. Nonetheless, there are critical gaps in the measurement of HL and in the evidence on the impact of inadequate HL on health outcomes, especially in the diabetes population. These gaps need to...
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Identification of Shared and Distinct Gene-disease Associations Among Multiple Related Diseases and Multiple Subtypes of a Disease
DownloadFall 2013
Genome-wide association study (GWAS) is an approach with high-throughput genotyping to uncover genetic susceptibilities of complex diseases. However, the genetic susceptibilities discovered usually carry very small risk increments. Additionally, the current approach to assess whether these...
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Impact of Introduction of Safety-Engineered Devices on the Incidence of Sharp Object Injury among Health Care Workers in the Capital Region of Alberta
DownloadFall 2012
Information on sharp object injuries occurring at work was obtained for a population of health care workers in the capital region of Alberta from Alberta Health Services to determine the incidence and characteristics of these injuries and the effectiveness of safety devices, introduced in...
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Individualized Health Related Quality of Life Measures: their use in children and their psychometric properties
DownloadFall 2012
Health related quality of life (HRQL) has recently been recognized as an essential outcome of patient-centered care. Individualized HRQL (iHRQL) measures propose a patient-centered approach to HRQL measurement; these measures allow patients to nominate areas of life that are important and then...
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Fall 2012
Parkinson’s disease (PD) involves the motor system and can lead to dementia. Dementia incidence among 102 non-demented participants (52 PD and 50 controls) followed prospectively over three years was assessed. Cognition was measured annually using the Clock Drawing Test (CDT), Mini-Mental State...
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Ocular gene transfer communications: Developing ethical frameworks for phase I choroideremia clinical trials
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I investigate how to ethically communicate about a phase I gene transfer trial for choroideremia, a blinding retinopathy, in light of this novel biotechnology’s portrayal as a potential ‘cure’. I analyzed gene transfer communications in three contexts: (1) interviews with clinicians (n=15),...
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Fall 2013
Physician training influences the care that a patient receives. A retrospective cohort of children over 6 years of age, seen in a multi-disciplinary asthma clinic between 2009 and 2010 and followed to 2012, was completed to identify differences in pediatric asthma management by physician...
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Quality indicators for patients presenting to emergency departments with cerebrovascular events: A chart review and prospective study of transient ischemic attacks and stroke within the Alberta Health Services-Edmonton Zone
DownloadSpring 2013
This thesis presents the results from a retrospective chart review of medical records and a prospective patient interview of stroke patients within the AHS Edmonton-Zone emergency departments. Of 7330 charts reviewed, 17% had a diagnosis other than stroke/TIA (misclassified). Of the 336 patients...