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- 1Adenoviral infection
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- 1Cardiac hypertrophy
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Fall 2010
The newborn heart possesses a higher tolerance to ischemia in comparison to adult hearts. Post-ischemic interventions that increase energy production are beneficial for recovery. These data suggest that the newborn heart holds on a very tight energetic plasticity and may not be capable to...
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Revisiting the antifibrinolytic effect of carboxypeptidase N: novel structure and regulation
DownloadFall 2010
Carboxypeptidase N (CPN) is a plasma carboxypeptidase that was discovered in the 1960s as a regulator of inflammation and vascular tone. Through the removal of carboxy-terminal basic residues, CPN alters the activity or binding specificity of inflammatory mediators and vasoactive peptides. CPN...
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The Association Between Neighbourhood Stressors and Asthma Prevalence of School Children in Winnipeg
DownloadSpring 2011
Neighbourhood stressors have an incubating effect for a variety of health-related disorders involving children. It is of interest is to determine if asthma prevalence is greater amongst school children at age 7-8 resident of chronic stress neighbourhoods in Winnipeg, after adjusting for family...
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Fall 2010
The mammalian Na+/H+ exchanger isoform 1 (NHE1) is a ubiquitously expressed membrane protein that regulates intracellular pH. In the myocardium, NHE1 has been implicated in ischemia/reperfusion (I/R) and cardiac hypertrophy (CH). Hormonal, autocrine and paracrine stimuli, acidosis, cardiotoxic...