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Skip to Search Results- 33Mass-spectrometry
- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Spring 2015
The objective of this work was to employ differential 13C/12C dansyl chloride (DnsCl) derivatization strategies for qualitative and quantitative profiling of amine- and phenol-containing metabolites by liquid chromatography electrospray ionization Fourier Transform ion cyclotron resonance mass...
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Fall 2018
Metabolomics is the ultimate reflection of organisms influenced by both genetic and environmental factors. Compared with other omics areas, it is the most appropriate and closest description of phenotype, which is the comprehensive characteristics of an organism. It is a powerful tool for global...
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Fall 2021
Metabolomics refers to the characterization and quantification of small molecule metabolic products in a biological specimen. It is an emerging and evolving science studying the practice of precious medicine. Metabolomics study has been used to understand individual variations influenced by both...
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Fall 2012
Mammalian glycoconjugates are composed exclusively of sugar in the thermodynamically favorable pyranose ring form; on the other hand, sugars in the five-membered furanose ring form are widespread in many bacteria, fungi, and protozoan pathogens. This makes the enzymes involved in furanoside...
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Chemical Synthesis and Biological Evaluation of Unusual Sulfur-Containing Peptides and Efforts Toward Chemical Synthesis of Crocin
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In order to minimize side reactions when preparing peptides containing a C-terminal cysteine residue, a method of protection of the carboxyl of the C-terminal cysteine as a cyclic ortho ester was developed. N-Fmoc-S-StBu cysteine cyclic ortho esters 31 (L) and 32 (D) were synthesized with...
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Chemical Synthesis to Understand and Influence Biological Systems: Spin Labels, Drug Development, and Biosynthetic Investigations
DownloadFall 2022
Spin labels are a useful tool towards the study of protein conformation and enable the mapping of interactions between specific positions within these systems. Synthetic routes towards three different chiral spin-labelled amino acids have been developed. Compared to commercially available spin...
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Chemical, Enzymatic and Chemo-enzymatic Synthesis of Complex Oligosaccharides as Probes of Glycan Functions
DownloadSpring 2016
Carbohydrates, an essential class of biomolecules, mediate a variety of biological processes. Recent advances in chemical, enzymatic and chemo-enzymatic synthesis have facilitated access to an increasing number of structurally well-defined oligosaccharides. These molecules are serving as...