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Effects of mechano-electrical feedback on cardiac dynamics: Pro- and anti-arrhythmic effects during alternans
DownloadSpring 2020
Contraction of the heart has been shown to affect the propagation of action potential (AP). In fact, the electrical waves of the heart propagate through the cardiac tissue and initiate its contraction via excitation-contraction coupling (ECC) while contraction of the heart causes deformations in...
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Fall 2014
The modelling of the electrical activity in cardiac tissue can enable researchers to study heart phenomena such as arrhythmias which are difficult to observe in vivo. However, the nature of the mathematical equations used to represent these behaviors present multiple numerical difficulties which...
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Spring 2021
For patients with decreased kidney function, waste materials accumulate within the blood compartment. Although not all of these chemical species have been directly linked to a specific toxicity, they are generally referred to as uremic toxins. Of particular interest are protein bound uremic...
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Spring 2024
Neural interfacing devices are designed to interact with the central nervous system to alleviate functional deficits in people with disabilities arising from neurological injuries or diseases. Such devices often involve the use of an invasive microelectrode implant which is designed to acutely...
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Fall 2012
Sonoporation, a physical, non-viral, non-chemical transfection method, promises great potentials. However, many drawbacks hinders its generalization. Low transfection rate and cell viability after treatment are among the hindering factors of sonoporation. The purpose of the research performed...