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An Investigation of the Oxidation of Carbohydrate versus Fat for Energy in Individuals with Type 2 DiabetesDownload
Impaired fat oxidation has been associated with increased plasma free fatty acid concentrations, ectopic fat deposition and insulin resistance, which may contribute to the development of Type 2 Diabetes (T2D). The objectives of this research were to determine whether individuals with T2D oxidized...
Assessment of the effectiveness of the Physical Activity and Nutrition for Diabetes in Alberta (PANDA) nutrition intervention for type 2 diabetes patientsDownload
Type 2 diabetes patients often find integrating a new dietary pattern into their lifestyle challenging; therefore, the PANDA (Physical Activity and Nutrition for Diabetes in Alberta) nutrition intervention was developed to help people incorporate the Canadian Diabetes Association (CDA) nutrition...
The overall purpose of this thesis was to identify determinants of quality of life in adults with diabetes mellitus. This thesis consists of two studies. The first study tested a comprehensive model which comprised of personal, medical and lifestyle factors to explain quality of life in adults...
Development and pilot test of a culturally tailored menu plan for Chinese immigrants with type 2 diabetesDownload
Chinese Canadians are at higher risk for developing diabetes than the general Canadian population. Although culturally tailored diabetes treatment is recommended, there is a lack of relevant dietary resources for Chinese in Canada. The objectives of this thesis were to identify components in...
The pathological events initiating diabetic cardiac changes in response to chronic hyperglycemia and hyperinsulinemia remain unclear. Due to the high metabolic activity of the heart, and its sensitivity to acute changes in oxygen and substrate flux, mitochondrial dysfunction has been proposed as...
Effects of dietary and pharmacological interventions on pancreatic β-cell compensation in Nile rats: a model for spontaneous type 2 diabetesDownload
Insulin-secreting pancreatic β-cells adapt to obesity-related insulin resistance via increases in insulin secretion and β-cell mass, which is referred to as β-cell compensation. Failed β-cell compensation predicts the onset of type 2 diabetes (T2D). However, the mechanisms underlying β-cell...
Gangliosides in Plasma and Chylomicrons of Control Participants and Individuals with Diabetes Fed both a High- and Low-Fat DietDownload
Aim: To investigate whether the plasma and chylomicron ganglioside profiles of participants with type 2 diabetes differ from those of matched control participants at 0, 2, 4, 6 and 8 hours postprandial when individuals are fed both a high- and low-fat diet for three days each. Background: Type 2...
Mental health and chronic medical conditions: schizophrenia, its treatment, risk of metabolic complications, and health care utilizationDownload
Objective - To assess the relationship between schizophrenia and cardiovascular disease by evaluating metabolic risk associated with treatment for schizophrenia, prevalence of cardiovascular risk factors (CV-RF) and disease (CV-D), and health care utilization in people with schizophrenia...
Menu planning and individual counseling as strategies to improve diet quality in people with type 2 diabetes: results from a pilot studyDownload
This 12-week study evaluated the effectiveness of menu planning and individual counseling in improving diet quality and health parameters among 15 type 2 diabetes patients using a pretest-posttest design. Perceived dietary adherence was measured and three-day food records were obtained to...
This thesis examines the economic and time barriers to dietary adherence for T2D patients living in Edmonton by using utility theory, household production theory and the concept of health capital. Socio-demographic, food consumption, food purchase and time use information was obtained by...