SearchSkip to Search Results
An examination of parent-child dyadic interaction and the impact of a parent-training program designed to support the language development of toddlers diagnosed with autism spectrum disorder (ASD)Download
Parents can effectively facilitate positive child behaviour change (Kaiser & Hancock, 2003). Their inclusion as interventionists is an essential component of autism intervention (NRC, 2001) and represents a natural step toward consistent early intervention. However, what constitutes effective...
Development and Analysis of Magnetic Carbon Nanotube and Microbubble-Assisted High Centrifugation Field Techniques For The Increase of Cell Membrane PermeabilityDownload
To cure diseases at the gene level, therapeutic biomaterials need to enter the cells. However, since the cell membrane is a highly selective structure, its permeability is usually very low. In this thesis, we propose two innovative and efficient methods to increase cell membrane permeability....
Proteins, which participate in virtually every process within cells, implement many of their functions through interactions with various ligands. Although a substantial effort in characterization and prediction of protein-ligand interactions was observed in the past two decades, these subjects...
In this thesis, measurement and analysis of colloidal forces between an atomic force microscope (AFM) probe and a topographically patterned substrate are reported. The energy between the patterned substrate and a smooth flat plate was characterized mathematically using Surface Element Integration...
Interactions Between Host Trees, Bacteria, and Fungi: Impacts on Mountain Pine Beetle (Dendroctonus ponderosae) ReproductionDownload
Warming winter trends due to climate change have allowed for a range expansion of the mountain pine beetle, and the beetle now threatens Canada’s economically and ecologically important jack pine forests. The beetle’s success in jack pine trees will depend upon successful colonization of the...
Interactions between Amyloid Precursor Protein and Prion Protein Impact Cell Adhesion and Apoptosis in the Developing ZebrafishDownload
We report here that knockdown of either amyloid precursor protein (APP) or prion protein (PrP) in the zebrafish produces an overt dose-dependent phenotype characterized by systemic morphological defects and CNS cell death. We report findings that the zebrafish PrP-1 gene genetically interacts...
Cellulose nanocrystals (CNCs) are an emerging renewable and sustainable nanomaterial which has received increasing attention. They are abundant, nontoxic, biodegradable and chemically inert. CNCs have unique characteristics not met by traditional cellulose-derived materials, leading...
Graphene has created much excitement in the scientific community since 2004, when Novoselov and Geim developed a method to exfoliate atomic layers from graphite, earning them the 2010 Nobel prize. The great interest in graphene stems from its outstanding material properties such as atomic...
Heterogeneity of surfaces is often included in mathematical treatments of colloid transport and deposition as an afterthought, if at all. Most previous models of colloid transport and deposition have employed idealizations and simplifications such as assuming smooth collector surfaces with...